dbPTM

NOP53_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NOP53_DROME
UniProt AC	Q9W3C2
Protein Name	Ribosome biogenesis protein NOP53 {ECO:0000305}
Gene Name	CG1785 {ECO:0000312\|EMBL:AAK92942.1}
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	478
Subcellular Localization	Nucleus, nucleolus . Nucleus, nucleoplasm .
Protein Description	May play a role in ribosome biogenesis, being required for integration of the 5S RNP into the ribosomal large subunit..
Protein Sequence	MTAVEPATKKKRISKKNKSAWRKTDIQDVEQFLEDQRQEERVGTFADKQDEDLFVVDSSLPKTKATVLSVKQKRKLNAKKPMRSYQALENTSKVQDPIAKRNHVRQKKNGRNIELEVCNPTKPRHRQANSDRAQYYVKLEQRLADKKNKKLDVEKDIWQEVDFRDEIPGLKDEKGWISRELALHTAGNIGKKVVKTHASLHHKTTKAKKFELPHPGMSYNPAPEDHQALIDQVVEREEGIIKKEQHLKRVTTSMFSKVTPEERDRRRLNEMSQGMDEEEGSELDEDVQTNGKKKEDDDEKPYHTINAPVENKKKSKQARRNELKQKELARQTELKRKLKQQTADLIRIKSIRHELDDEEEDLNDLKKRRKQRAEKAKFEPKRLGRHKFEEPDLDVNLPEDIAGNLRNVKTESSLLKDRFHTLQRNNMLPTTKLVSRKKSKVKRFERNSHKEPGVSYNDLKERRRAAAAAAKATANIKI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
281	Phosphorylation	GMDEEEGSELDEDVQ CCCHHHCCCCCHHHH		19429919
289	Phosphorylation	ELDEDVQTNGKKKED CCCHHHHHCCCCCCC		22668510

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of NOP53_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NOP53_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NOP53_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NOP53_DROME

Related Literatures of Post-Translational Modification