dbPTM

NOP14_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NOP14_DROME
UniProt AC	Q9VEJ2
Protein Name	Nucleolar protein 14 homolog
Gene Name	l(3)07882
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	852
Subcellular Localization	Nucleus, nucleolus.
Protein Description	Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity)..
Protein Sequence	MVAKGKKASADAVYAKKTTRSANPFDNSTAQSSKRGNPFDVHVNKEKFKILGRICKHDRGMPGVSRAKALQKRAQTLGQQFAVKHKTNRFKDNRIGKHLSGDQLTESVMNARYLAEKMSQVRSNQKAEKFNLNDDELLTHRGQTLEEIEQYRDERSDDEELDDEALDADFTAAAHFGGEGDSAQDRQAAIDEMIVEQKRRKNEIAKEKDEVYDLTEKLDANYKLLLPLVAKVTKDEQDAKPPPDAYDKLLKEMIFEPRGSVADKLINPDELAKQEAARLEKLENERLRRMRADGEEDEEASVAKPKHRSADDLDDGYFLAGEDDEGDDTLAYDLDGNLGTHLNGKKEAVLKGDENEDDDDKEGEEEEEEDSDEESDSEVDNLSDLKESESESEPEEAPKASKKKAKKSADTIPASLDTSIPFTIKMPKTYEDFTELLSKHATAQKAIIIERIIKCNHPKLEGVNRENVVKLYSFLLQYLKDLFEDASEQDIREHFQLLSKLMPYLYELTQLNPERMSNTLLEVIKEKYEEFRKNHKMYPSLDTLVYFKLVANLYSTSDFRHPVVTPCFIFIQHVLSRSRVRTRQEISMGLFLVTVVLEFVSQSKRLVPAVFNFLQGIVHMSIPKRDVEQLEITPPFERDGPLSKLLALPANTESTKLEPQQLQPTDLVTQTITPDFKVRALDTSLLLIKEALQLVEEHVGACYLAQPFLALLSRLPLESYPEHVHQHHKDATELAEKLAAQKMKPLAPAEKKPKALRLLEPRFEAVYDDKRRPKMSKAKEERAKLLHKIKREKKGAIREIRRDTSFVQMLRLKQTLQSDKERHEKVKRIYQEASVQQGELNELSRAKKKKKF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
156	Phosphorylation	EQYRDERSDDEELDD HHHHHHCCCCHHCCH	47.57	19429919
171	Phosphorylation	EALDADFTAAAHFGG HHHCCHHHHHHHHCC	18.88	22668510
805	Phosphorylation	REIRRDTSFVQMLRL HHHHCCCCHHHHHHH	27.92	21082442

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of NOP14_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NOP14_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NOP14_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of NOP14_DROME !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NOP14_DROME

Related Literatures of Post-Translational Modification