NOM1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NOM1_MOUSE
• UniProt AC: Q3UFM5
• Protein Name: Nucleolar MIF4G domain-containing protein 1
• Gene Name: Nom1
• Organism: Mus musculus (Mouse).
• Sequence Length: 854
• Subcellular Localization: Nucleus, nucleolus.
• Protein Description: Plays a role in targeting PPP1CA to the nucleolus..
• Protein Sequence: MPRNVPEVNGVYRHGACELWCRAMAHALLKRSGVRRGLGGREGPLKRLRLAVEDFVRTTSESEACESRSAVARSRPGGRKSRKELRKEKRHLRKARRLQRTVGSGSGDQGGNVGLNDGPETRRPPTEVRPTPAKATATPAKASAPSTNTKASAAQPKAKAKGAPGKPGPATATARKRALLAANEEEDREIRKLERCLGLHKRKKKGDGSSVPLSFARDGLDYILGALECGSGGGLYESSEEEEEEKLETGQTVLESDLESNSKESEEDPDWQVLQEDQEDVNSKRRGEAESGTRGNKGTKKVRFAEVVEKSRSSSEDDIEQQESHSVESGEKYIPPRLRNEEVIDVHKKEELDRLKKHVKGLINRLSEPNMASISGQLEELYMAHSRKDMNDTLTTALMDACVTASAMPSRLMMEHVFLVSILHHTVGIEVGACFLEAVVKKFDAIYRDGGEGKELDNLFTMIAHLYNFHVVQSILIFDILKKLVGTFTEKDIELILLMLKNVGFALRKDDALSLKELITEAQTQASGAGNKFQDQNRVRFMLETMLALKNNDLRKIPGYNPEPVEKLKKLQRTLVRNAGSGSETRLRISWDGILNAEQTGRWWIVGSAWSGTPMIDNSHHIQLQKPLAGMASSKMLELARKQRMNTDVRRIIFCTLMTSEDFLDAFEKLLKLGLKDQQEREIVHILMDCCLQEKTYNPFYAFLASKFCDYERRFQMTFQFSIWDKFRDLENLPDTKFSNLVHLLAHLLRTKSLPLSVLKVVEFSELDKPRVHFLRRVLTALLMETEDDDLAVIFSRVSDNPKLGMLREGLKLFIGHFLLKHTQAHQSAEEASLLREKAGLASKSLQGKAILRM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
58	Phosphorylation	AVEDFVRTTSESEAC HHHHHHHHCCHHHHH	29.40	26745281
59	Phosphorylation	VEDFVRTTSESEACE HHHHHHHCCHHHHHH	21.67	26745281
60	Phosphorylation	EDFVRTTSESEACES HHHHHHCCHHHHHHH	38.21	29514104
62	Phosphorylation	FVRTTSESEACESRS HHHHCCHHHHHHHHH	30.20	26745281
136	Phosphorylation	RPTPAKATATPAKAS CCCCCCCCCCCCCCC	30.29	28059163
149	Phosphorylation	ASAPSTNTKASAAQP CCCCCCCCCCCCCCC	28.24	28059163
231	Phosphorylation	LGALECGSGGGLYES HHHHHCCCCCCCCCC	46.02	29550500
236	Phosphorylation	CGSGGGLYESSEEEE CCCCCCCCCCCHHHH	19.62	29550500
238	Phosphorylation	SGGGLYESSEEEEEE CCCCCCCCCHHHHHH	29.50	29550500
239	Phosphorylation	GGGLYESSEEEEEEK CCCCCCCCHHHHHHH	36.77	29550500
249	Phosphorylation	EEEEKLETGQTVLES HHHHHHHHCCHHHHH	45.05	26643407
252	Phosphorylation	EKLETGQTVLESDLE HHHHHCCHHHHHHHH	28.53	26643407
256	Phosphorylation	TGQTVLESDLESNSK HCCHHHHHHHHCCCC	43.25	26643407
260	Phosphorylation	VLESDLESNSKESEE HHHHHHHCCCCCCCC	54.42	22817900
262	Phosphorylation	ESDLESNSKESEEDP HHHHHCCCCCCCCCC	47.26	22817900
265	Phosphorylation	LESNSKESEEDPDWQ HHCCCCCCCCCCCCH	50.45	28973931
311	Phosphorylation	FAEVVEKSRSSSEDD HHHHHHHHCCCCHHH	24.72	21149613
313	Phosphorylation	EVVEKSRSSSEDDIE HHHHHHCCCCHHHHH	45.36	27087446
314	Phosphorylation	VVEKSRSSSEDDIEQ HHHHHCCCCHHHHHH	36.31	27087446
315	Phosphorylation	VEKSRSSSEDDIEQQ HHHHCCCCHHHHHHH	46.41	27087446
324	Phosphorylation	DDIEQQESHSVESGE HHHHHHHHHCCCCCC	19.41	26643407
326	Phosphorylation	IEQQESHSVESGEKY HHHHHHHCCCCCCCC	36.54	25159016
329	Phosphorylation	QESHSVESGEKYIPP HHHHCCCCCCCCCCC	50.53	26643407
736	Phosphorylation	DLENLPDTKFSNLVH CHHCCCCCCHHHHHH	31.86	28066266

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NOM1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NOM1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NOM1_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of NOM1_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.