dbPTM

NOG2_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NOG2_SCHPO
UniProt AC	O14236
Protein Name	Nucleolar GTP-binding protein 2
Gene Name	nog2
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	537
Subcellular Localization	Nucleus, nucleolus .
Protein Description	GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation..
Protein Sequence	MGTYKKEKSRIGREGANEKKPGNLRVKGENFYRNAKDVARVNMYRGGKAKYNAAGELVRAAEFQSSEVPKARIQPDRRWFNNTRVIAQPTLTQFREAMGQKLNDPYQVLLRRNKLPMSLLQENTEIPKVRVLESEPFENTFGPKSQRKRPKISFDSVAELAKESDEKQNAYEEKIEERILANPDESDDVMLAARDAIFSKGQSKRIWNELYKVIDSSDVLIQVLDARDPVGTRCGTVERYLRNEASHKHMILVLNKVDLVPTSVAAAWVKILAKEYPTIAFHASINNSFGKGSLIQILRQFASLHSDKKQISVGLIGFPNAGKSSIINTLRKKKVCNVAPIPGETKVWQYVALMKRIFLIDCPGIVPPSSNDSDAELLLKGVVRVENVSNPEAYIPTVLSRCKVKHLERTYEISGWNDSTEFLAKLAKKGGRLLKGGEPDEASVAKMVLNDFMRGKIPWFIGPKGLSSSNDEINSSQKVATQQTEGSDQDGEEAEEEWHGISDDGKADESESTKPVAEGSASESTDESAVDDNKNRS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
153	Phosphorylation	QRKRPKISFDSVAEL HCCCCCCCHHHHHHH	29.18	28889911
186	Phosphorylation	ILANPDESDDVMLAA HHHCCCCCCHHHHHH	46.63	28889911
476	Phosphorylation	SNDEINSSQKVATQQ CCCCCHHHHHHHHHC	29.54	29996109
481	Phosphorylation	NSSQKVATQQTEGSD HHHHHHHHHCCCCCC	24.97	29996109
484	Phosphorylation	QKVATQQTEGSDQDG HHHHHHCCCCCCCCH	32.28	28889911
487	Phosphorylation	ATQQTEGSDQDGEEA HHHCCCCCCCCHHHH	26.35	28889911
502	Phosphorylation	EEEWHGISDDGKADE HHHHCCCCCCCCCCC	33.95	24763107
510	Phosphorylation	DDGKADESESTKPVA CCCCCCCCCCCCCCC	37.08	27738172
520	Phosphorylation	TKPVAEGSASESTDE CCCCCCCCCCCCCCH	21.81	24763107
522	Phosphorylation	PVAEGSASESTDESA CCCCCCCCCCCCHHH	33.50	24763107
524	Phosphorylation	AEGSASESTDESAVD CCCCCCCCCCHHHCC	38.37	24763107
525	Phosphorylation	EGSASESTDESAVDD CCCCCCCCCHHHCCC	39.47	29996109
528	Phosphorylation	ASESTDESAVDDNKN CCCCCCHHHCCCCCC	36.08	29996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of NOG2_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NOG2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NOG2_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of NOG2_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NOG2_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-186; THR-484 ANDSER-487, AND MASS SPECTROMETRY.	18257517 [Abstract]