NOG1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NOG1_MOUSE
• UniProt AC: Q99ME9
• Protein Name: Nucleolar GTP-binding protein 1
• Gene Name: Gtpbp4
• Organism: Mus musculus (Mouse).
• Sequence Length: 634
• Subcellular Localization: Nucleus, nucleolus.
• Protein Description: Involved in the biogenesis of the 60S ribosomal subunit..
• Protein Sequence: MAHYNFKKITVVPSAKDFIDLTLSKTQRKTPTVIHKHYQIHRIRHFYMRKVKFTQQNYHDRLSQILSDFPKLDDIHPFYADLMNILYDKDHYKLALGQINIAKNLVDNVAKDYVRLMKYGDSLYRCKQLKRAALGRMCTIIKRQRQSLEYLEQVRQHLSRLPTIDPNTRTLLLCGYPNVGKSSFINKVTRADVDVQPYAFTTKSLFVGHMDYKYLRWQVVDTPGILDHPLEDRNTIEMQAITALAHLRAAVLYVMDLSEQCGHGLKEQLELFQNIRPLFINKPLIVVANKCDVKRIAELSEEDQKIFLDLQAEGFPVIETSTLTEEGVIQVKTEACDRLLAHRVETKMKGNKVNEVLNRLHLAVPNKRDDKERPPFIPEGVIARRKRMEIEEPKKKRERDLELEMGDDYILDLQKYWDLMNSSEKYDKIPEIWEGHNVADYIDPAIMKKLEELEKEEELRTAAGEYDSDSESEDEEMMEIRQLAKQIREKKKLKILQSKEKNKQGPRMPRTAKKVQRADLENEMRSLGVDMDDKNNAHYAVQARRSRSVTRKRKREESVPPSSTARSRSCSRTPRDVSGLRDVKMVKKAKTMMKKAQKKMNRLGKKGEADRHVFDMKPKHLLSGKRKAGKKDRR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MAHYNFKKI ------CCCCCCCEE	17.55	-
103	Acetylation	LGQINIAKNLVDNVA HHHHHHHHHHHHHHH	47.20	-
113	Phosphorylation	VDNVAKDYVRLMKYG HHHHHHHHHHHHHHC	6.17	29514104
122	Phosphorylation	RLMKYGDSLYRCKQL HHHHHCCHHHHHHHH	23.96	29176673
409	Phosphorylation	ELEMGDDYILDLQKY CCCCCCCEEHHHHHH	14.23	25159016
461	Phosphorylation	EKEEELRTAAGEYDS HHHHHHHHHCCCCCC	33.22	23429704
466	Phosphorylation	LRTAAGEYDSDSESE HHHHCCCCCCCCCCC	21.59	23684622
468	Phosphorylation	TAAGEYDSDSESEDE HHCCCCCCCCCCCCH	41.98	27087446
470	Phosphorylation	AGEYDSDSESEDEEM CCCCCCCCCCCCHHH	47.15	27087446
472	Phosphorylation	EYDSDSESEDEEMME CCCCCCCCCCHHHHH	55.06	27087446
558	Phosphorylation	RKRKREESVPPSSTA CHHHHHHCCCCCCCC	34.86	23970565
564	Phosphorylation	ESVPPSSTARSRSCS HCCCCCCCCCCCCCC	30.35	22942356
572	Methylation	ARSRSCSRTPRDVSG CCCCCCCCCCCCCCC	53.74	-
578	Phosphorylation	SRTPRDVSGLRDVKM CCCCCCCCCCCHHHH	36.08	26824392

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NOG1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NOG1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NOG1_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of NOG1_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.