dbPTM

NMBR_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NMBR_HUMAN
UniProt AC	P28336
Protein Name	Neuromedin-B receptor
Gene Name	NMBR
Organism	Homo sapiens (Human).
Sequence Length	390
Subcellular Localization	Cell membrane Multi-pass membrane protein.
Protein Description	Receptor for neuromedin-B..
Protein Sequence	MPSKSLSNLSVTTGANESGSVPEGWERDFLPASDGTTTELVIRCVIPSLYLLIITVGLLGNIMLVKIFITNSAMRSVPNIFISNLAAGDLLLLLTCVPVDASRYFFDEWMFGKVGCKLIPVIQLTSVGVSVFTLTALSADRYRAIVNPMDMQTSGALLRTCVKAMGIWVVSVLLAVPEAVFSEVARISSLDNSSFTACIPYPQTDELHPKIHSVLIFLVYFLIPLAIISIYYYHIAKTLIKSAHNLPGEYNEHTKKQMETRKRLAKIVLVFVGCFIFCWFPNHILYMYRSFNYNEIDPSLGHMIVTLVARVLSFGNSCVNPFALYLLSESFRRHFNSQLCCGRKSYQERGTSYLLSSSAVRMTSLKSNAKNMVTNSVLLNGHSMKQEMAL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
8	N-linked_Glycosylation	MPSKSLSNLSVTTGA CCCCCCCCCEEECCC	41.45	UniProtKB CARBOHYD
16	N-linked_Glycosylation	LSVTTGANESGSVPE CEEECCCCCCCCCCC	45.36	UniProtKB CARBOHYD
130	Phosphorylation	QLTSVGVSVFTLTAL EEECCCEEEEHHHHH	12.94	-
192	N-linked_Glycosylation	ARISSLDNSSFTACI HHHHHCCCCCCEEEE	44.86	UniProtKB CARBOHYD
286	Phosphorylation	WFPNHILYMYRSFNY HCHHHHHHHHHHCCC	7.47	-
288	Phosphorylation	PNHILYMYRSFNYNE HHHHHHHHHHCCCCC	6.91	-
341	S-palmitoylation	HFNSQLCCGRKSYQE HCCCCCCCCCCCHHH	8.86	-
351	Phosphorylation	KSYQERGTSYLLSSS CCHHHHCCHHHHCCH	22.03	22817900
352	Phosphorylation	SYQERGTSYLLSSSA CHHHHCCHHHHCCHH	19.33	22817900
356	Phosphorylation	RGTSYLLSSSAVRMT HCCHHHHCCHHHHHH	21.47	-
374	Phosphorylation	SNAKNMVTNSVLLNG HHHHHHCHHHHHHCC	15.82	24260401
376	Phosphorylation	AKNMVTNSVLLNGHS HHHHCHHHHHHCCCC	12.55	24260401

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of NMBR_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NMBR_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NMBR_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of NMBR_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NMBR_HUMAN

Related Literatures of Post-Translational Modification