dbPTM

NLE1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NLE1_SCHPO
UniProt AC	O74855
Protein Name	Ribosome assembly protein 4 {ECO:0000250\|UniProtKB:P25382}
Gene Name	rsa4
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	502
Subcellular Localization	Nucleus, nucleolus .
Protein Description	Involved in ribosome biogenesis. Required for processing and efficient intra-nuclear transport of pre-60S ribosomal subunits. Interacts with the AAA-ATPase Midasin, which is essential for the ATP-dependent dissociation of a group of nonribosomal factors from the pre-60S particle..
Protein Sequence	MATLLPPKSKRQKKESLNPTTIEIPEKFPLVNVQFRASDDSNELASLLVPGNSSVRQLEALLNQLLENSDDPVPYNFALHHEDETIEIQDNLYTSVFHNGLMKTEDHLTLLYTPQAVFRVRAVTRCTASMNGHDGTIISAQFSPSTSSRLVTGSGDFTARLWDCDTQTPIATMKGHTNWVSCVAWAPDASIIATGSMDNTIRFWDPKKGSPIGDALRRHTKPIMALCWQPLHLAPDSGPYLLASGSKDNTVRIWNVKLRTLLFTLSGHTAPITCVRWGGQNWIYSSSYDKTIRIWDAKDGKCLHILKGHAARVNHLSLSTEHVLRSGAYDHTDFKPKSFSDERRKAKERYEACLKQSGERLVSASDDLQLILWDPQKSTKPITKMHGHQKVVNHASFSPDGRCIATASFDSSVRLWDGKTGKFLATLRGHVAAVYQCAWSTDSRLLVSSSQDTTLKVWDVRSKKMKFDLPGHEDQVFAVDWSPDGQRVASGGADKAVRIWSH

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
16	Phosphorylation	SKRQKKESLNPTTIE CHHHCCCCCCCCEEE	42.18	24763107

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of NLE1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NLE1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NLE1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of NLE1_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NLE1_SCHPO

Related Literatures of Post-Translational Modification