NIR_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NIR_ARATH
• UniProt AC: Q39161
• Protein Name: Ferredoxin--nitrite reductase, chloroplastic
• Gene Name: NIR1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 586
• Subcellular Localization: Plastid, chloroplast .
• Protein Description: Catalyzes the six-electron reduction of nitrite to ammonium..
• Protein Sequence: MTSFSLTFTSPLLPSSSTKPKRSVLVAAAQTTAPAESTASVDADRLEPRVELKDGFFILKEKFRKGINPQEKVKIEREPMKLFMENGIEELAKKSMEELDSEKSSKDDIDVRLKWLGLFHRRKHQYGKFMMRLKLPNGVTTSAQTRYLASVIRKYGEDGCADVTTRQNWQIRGVVLPDVPEILKGLASVGLTSLQSGMDNVRNPVGNPIAGIDPEEIVDTRPYTNLLSQFITANSQGNPDFTNLPRKWNVCVVGTHDLYEHPHINDLAYMPANKDGRFGFNLLVGGFFSPKRCEEAIPLDAWVPADDVLPLCKAVLEAYRDLGTRGNRQKTRMMWLIDELGVEGFRTEVEKRMPNGKLERGSSEDLVNKQWERRDYFGVNPQKQEGLSFVGLHVPVGRLQADDMDELARLADTYGSGELRLTVEQNIIIPNVETSKTEALLQEPFLKNRFSPEPSILMKGLVACTGSQFCGQAIIETKLRALKVTEEVERLVSVPRPIRMHWTGCPNTCGQVQVADIGFMGCLTRGEEGKPVEGADVYVGGRIGSDSHIGEIYKKGVRVTELVPLVAEILIKEFGAVPREREENED

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
80	Sulfoxidation	VKIEREPMKLFMENG CCCCCHHHHHHHHHC	5.16	25693801
96	Sulfoxidation	EELAKKSMEELDSEK HHHHHHHHHHHHHCC	6.78	25693801
103	Ubiquitination	MEELDSEKSSKDDID HHHHHHCCCCHHHHH	65.07	17272265
362	Phosphorylation	NGKLERGSSEDLVNK CCCCCCCCHHHHHHH	36.45	25561503
363	Phosphorylation	GKLERGSSEDLVNKQ CCCCCCCHHHHHHHH	37.64	25561503
404	Sulfoxidation	GRLQADDMDELARLA CCCCCCCHHHHHHHH	4.43	23289948
413	Phosphorylation	ELARLADTYGSGELR HHHHHHHHHCCCEEE	24.95	19880383
458	Sulfoxidation	SPEPSILMKGLVACT CCCCCHHHCCCEEEC	2.85	25693801

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NIR_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NIR_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NIR_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of NIR_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Ubiquitylation

"Multidimensional protein identification technology (MudPIT) analysisof ubiquitinated proteins in plants.";
Maor R., Jones A., Nuehse T.S., Studholme D.J., Peck S.C., Shirasu K.;
Mol. Cell. Proteomics 6:601-610(2007).
Cited for: UBIQUITINATION [LARGE SCALE ANALYSIS] AT LYS-103, AND MASSSPECTROMETRY.
PubMed: 17272265