NIPS1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NIPS1_MOUSE
• UniProt AC: O55125
• Protein Name: Protein NipSnap homolog 1
• Gene Name: Nipsnap1
• Organism: Mus musculus (Mouse).
• Sequence Length: 284
• Protein Sequence: MAPRLCIISAAARRLFTKPRPRAGDLAAAGAVRFYSKDSEGSWFRSLFVHKVDPRKDAHSTLLSKKETSNLYKIQFHNVKPECLDAYNSLTEAVLPKLHLDEDYPCSLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLKNNKEYLEFRKERSKMLLSRRNQLLLEFSFWNEPQPRAGPNIYELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDENVYYTVPLVRHMESRIMIPLKISPLQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
37	Acetylation	GAVRFYSKDSEGSWF CEEEEEECCCCCCEE	54.62	23576753
51	Acetylation	FRSLFVHKVDPRKDA EEEEEEEECCCCCCH	42.93	23864654
56	Malonylation	VHKVDPRKDAHSTLL EEECCCCCCHHHHHC	65.73	26320211
56	Glutarylation	VHKVDPRKDAHSTLL EEECCCCCCHHHHHC	65.73	24703693
65	Acetylation	AHSTLLSKKETSNLY HHHHHCCHHHCCCCE	55.38	23576753
66	Malonylation	HSTLLSKKETSNLYK HHHHCCHHHCCCCEE	63.95	26320211
66	Acetylation	HSTLLSKKETSNLYK HHHHCCHHHCCCCEE	63.95	23576753
73	Acetylation	KETSNLYKIQFHNVK HHCCCCEEEEEECCC	32.95	23576753
80	Acetylation	KIQFHNVKPECLDAY EEEEECCCHHHHHHH	40.18	23576753
83	S-nitrosocysteine	FHNVKPECLDAYNSL EECCCHHHHHHHHHH	5.90	-
83	Glutathionylation	FHNVKPECLDAYNSL EECCCHHHHHHHHHH	5.90	24333276
83	S-palmitoylation	FHNVKPECLDAYNSL EECCCHHHHHHHHHH	5.90	28526873
83	S-nitrosylation	FHNVKPECLDAYNSL EECCCHHHHHHHHHH	5.90	20925432
87	Phosphorylation	KPECLDAYNSLTEAV CHHHHHHHHHHHHHH	12.64	23984901
89	Phosphorylation	ECLDAYNSLTEAVLP HHHHHHHHHHHHHHH	24.80	25521595
91	Phosphorylation	LDAYNSLTEAVLPKL HHHHHHHHHHHHHHC	23.01	23984901
129	Phosphorylation	AVHLWRFSGGYPALM CEEEEEECCCHHHHH	23.80	25521595
132	Phosphorylation	LWRFSGGYPALMDCM EEEECCCHHHHHHHH	6.72	23140645
138	S-palmitoylation	GYPALMDCMNKLKNN CHHHHHHHHHHHHCC	1.70	28526873
141	Acetylation	ALMDCMNKLKNNKEY HHHHHHHHHHCCHHH	33.67	23864654
143	Acetylation	MDCMNKLKNNKEYLE HHHHHHHHCCHHHHH	61.15	23576753
146	Succinylation	MNKLKNNKEYLEFRK HHHHHCCHHHHHHHH	58.07	-
146	Succinylation	MNKLKNNKEYLEFRK HHHHHCCHHHHHHHH	58.07	23806337
146	Acetylation	MNKLKNNKEYLEFRK HHHHHCCHHHHHHHH	58.07	23576753
146	Glutarylation	MNKLKNNKEYLEFRK HHHHHCCHHHHHHHH	58.07	24703693
148	Phosphorylation	KLKNNKEYLEFRKER HHHCCHHHHHHHHHH	17.09	26032504
152	Methylation	NKEYLEFRKERSKML CHHHHHHHHHHHHHH	30.47	30988655
155	Methylation	YLEFRKERSKMLLSR HHHHHHHHHHHHHHH	44.61	30988661
157	Malonylation	EFRKERSKMLLSRRN HHHHHHHHHHHHHHH	39.53	26320211
191	Glutarylation	IYELRTYKLKPGTMI EEEEEEEECCCCCEE	49.80	24703693
191	Acetylation	IYELRTYKLKPGTMI EEEEEEEECCCCCEE	49.80	23576753
191	Succinylation	IYELRTYKLKPGTMI EEEEEEEECCCCCEE	49.80	23806337
193	Glutarylation	ELRTYKLKPGTMIEW EEEEEECCCCCEEEE	36.93	24703693
193	Acetylation	ELRTYKLKPGTMIEW EEEEEECCCCCEEEE	36.93	23576753
193	Succinylation	ELRTYKLKPGTMIEW EEEEEECCCCCEEEE	36.93	-
193	Succinylation	ELRTYKLKPGTMIEW EEEEEECCCCCEEEE	36.93	23806337
238	Acetylation	VHHLWAYKDLQSREE HEEHHHHHCHHCHHH	44.19	23954790
261	Phosphorylation	RGWDENVYYTVPLVR CCCCCCCEEEHHHEE	12.66	26032504
262	Phosphorylation	GWDENVYYTVPLVRH CCCCCCEEEHHHEEE	9.29	23140645
263	Phosphorylation	WDENVYYTVPLVRHM CCCCCEEEHHHEEEC	9.65	23984901
279	Acetylation	SRIMIPLKISPLQ-- CEEEEEEEECCCC--	35.46	23576753
279	Succinylation	SRIMIPLKISPLQ-- CEEEEEEEECCCC--	35.46	24315375

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NIPS1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NIPS1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NIPS1_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of NIPS1_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.