NIBL1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NIBL1_MOUSE
• UniProt AC: Q8R1F1
• Protein Name: Niban-like protein 1
• Gene Name: Fam129b
• Organism: Mus musculus (Mouse).
• Sequence Length: 749
• Subcellular Localization: Cytoplasm, cytosol . Cell junction, adherens junction. Membrane ; Lipid-anchor . In exponentially growing cells, exclusively cytoplasmic. Cell membrane localization is observed when cells reach confluency and during telophase (By similarity). Phospho
• Protein Description: May play a role in apoptosis suppression..
• Protein Sequence: MGDVLSTHLDDARRQHIAEKTEKILTEFLRFYEDQYGVSLFNSMRHEIEGTGPPQAQLLWRKVPLDERIIFSGNLFQYQEDNKKWRNRFSLVPHNYGLVLYENKVAYERQIPPRAVINSAGYKVLTSVDQYLELVGNSLPGTTSKSGSTPILKCPTQFPLILWHPYARHYYFCMMTEAEQDKWQAVLQDCVRHCNNGIPENSKVEGPAFTDAIRMYRQSKEQYGTWEMLCGNEVQILSNLVMEELGPALKAELGPRLKGKPQERQRQWIQISDAVYRLVFEQAKVHFEDVLCKLQRARPAMEAVIRTDMDQIITSKEHLASKIRAFILPKAEVCVRNHVQPYIPSILEALMVPTSQGFTEVRDVFFKEVTDMNLNVINEGGIDKLGEYMEKLSQLAYHPLKMQSCYEKMEPLRLDGLQQRFDVSSTSVFKQRAQIHMREQMDNAVYTFETLLHQELGKGPTKEELCKSIQRILERVLKKYDYDSSSVRKRFFREALLQITIPFLLKKLAPTCKSELPRFQELIFEDFARFILVENTYEEVVLQTVMKDILQAVKEAAVQRKHNLYRDSMVLHNSDPNLHLLAEGTPIDWGEQYGDSGDSGGGDSGGSPCPSEAATLTEKRRRAKQVMSVVQDEESGLPFEAGVEPPSPASPDSVTELRGLLAQDLQAESSPPASPLLNGAPVQESSQPVAVPEASPPASPLRHLPPGKAVDLEPPKPSDQETGEQVSSPGSRPPIHTTTEDSAGVQTEF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
154	S-nitrosylation	GSTPILKCPTQFPLI CCCCCCCCCCCCCEE	3.85	20925432
334	Glutathionylation	ILPKAEVCVRNHVQP HCCCHHHHHHCCCCC	1.47	24333276
512	Glutathionylation	LKKLAPTCKSELPRF HHHHHHHCCHHCHHH	4.43	24333276

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NIBL1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NIBL1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NIBL1_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NIBL1_HUMAN	FAM129B	physical	20360068

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.