dbPTM

NHSL1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NHSL1_HUMAN
UniProt AC	Q5SYE7
Protein Name	NHS-like protein 1
Gene Name	NHSL1
Organism	Homo sapiens (Human).
Sequence Length	1610
Subcellular Localization
Protein Description
Protein Sequence	MKKEGSSGSFRLQPNTGSLSRAVSWINFSSLSRQTKRLFRSDGELSVCGQQVEVDDENWIYRAQPRKAVSNLDEESRWTVHYTAPWHQQENVFLPTTRPPCVEDLHRQAKLNLKSVLRECDKLRHDGYRSSQYYSQGPTFAANASPFCDDYQDEDEETDQKCSLSSSEEERFISIRRPKTPASSDFSDLNTQTNWTKSLPLPTPEEKMRQQAQTVQADVVPINITASGTGQDDADGHSVYTPDHYSTLGRFNSCRSAGQRSETRDSSCQTEDVKVVPPSMRRIRAQKGQGIAAQMGHFSGSSGNMSVLSDSAGIVFPSRLDSDAGFHSLPRSGARANIQSLEPRLGALGPAGDMNGTFLYQRGHPQADENLGHLGGASGTGTLLRPKSQELRHFESENIMSPACVVSPHATYSTSIIPNATLSSSSEVIAIPTAQSAGQRESKSSGSSHARIKSRDHLISRHAVKGDPQSPGRHWNEGHATILSQDLDPHSPGEPALLSLCDSAVPLNAPANRENGSQAMPYNCRNNLAFPAHPQDVDGKSESSYSGGGGHSSSEPWEYKSSGNGRASPLKPHLATPGYSTPTSNMSSCSLDQTSNKEDAGSLYSEDHDGYCASVHTDSGHGSGNLCNSSDGFGNPRHSVINVFVGRAQKNQGDRSNYQDKSLSRNISLKKAKKPPLPPSRTDSLRRIPKKSSQCNGQVLNESLIATLQHSLQLSLPGKSGSSPSQSPCSDLEEPWLPRSRSQSTVSAGSSMTSATTPNVYSLCGATPSQSDTSSVKSEYTDPWGYYIDYTGMQEDPGNPAGGCSTSSGVPTGNGPVRHVQEGSRATMPQVPGGSVKPKIMSPEKSHRVISPSSGYSSQSNTPTALTPVPVFLKSVSPANGKGKPKPKVPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQEEPAENSADTGGDGESCLSQQDGAAGVPETNAAGSSSEACDFLKEDGNDEVMTPSRPRTTEDLFAAIHRSKRKVLGRRDSDDDHSRNHSPSPPVTPTGAAPSLASPKQVGSIQRSIRKSSTSSDNFKALLLKKGSRSDTSARMSAAEMLKNTDPRFQRSRSEPSPDAPESPSSCSPSKNRRAQEEWAKNEGLMPRSLSFSGPRYGRSRTPPSAASSRYSMRNRIQSSPMTVISEGEGEAVEPVDSIARGALGAAEGCSLDGLAREEMDEGGLLCGEGPAASLQPQAPGPVDGTASAEGREPSPQCGGSLSEES

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
16	Phosphorylation	SFRLQPNTGSLSRAV CEECCCCCCCHHHHH	34.53	29255136
18	Phosphorylation	RLQPNTGSLSRAVSW ECCCCCCCHHHHHHE	22.57	24719451
20	Phosphorylation	QPNTGSLSRAVSWIN CCCCCCHHHHHHEEC	21.64	29255136
24	Phosphorylation	GSLSRAVSWINFSSL CCHHHHHHEECHHHH	22.66	22617229
130	Phosphorylation	LRHDGYRSSQYYSQG HCCCCCCCHHCCCCC	17.20	30576142
151	Phosphorylation	ASPFCDDYQDEDEET CCCCCCCCCCCCHHH	12.47	-
163	Phosphorylation	EETDQKCSLSSSEEE HHHCCCCCCCCCHHH	38.02	27794612
165	Phosphorylation	TDQKCSLSSSEEERF HCCCCCCCCCHHHHH	18.61	29255136
166	Phosphorylation	DQKCSLSSSEEERFI CCCCCCCCCHHHHHH	47.24	29255136
167	Phosphorylation	QKCSLSSSEEERFIS CCCCCCCCHHHHHHE	45.73	29255136
174	Phosphorylation	SEEERFISIRRPKTP CHHHHHHEECCCCCC	13.82	24719451
177 (in isoform 2)	Phosphorylation	-	35.08	24719451
180	Phosphorylation	ISIRRPKTPASSDFS HEECCCCCCCCCCCH	27.11	25849741
183	Phosphorylation	RRPKTPASSDFSDLN CCCCCCCCCCCHHCC	31.48	30576142
184	Phosphorylation	RPKTPASSDFSDLNT CCCCCCCCCCHHCCC	44.79	25850435
186 (in isoform 2)	Phosphorylation	-	7.08	27282143
187	Phosphorylation	TPASSDFSDLNTQTN CCCCCCCHHCCCCCC	46.29	30576142
190 (in isoform 2)	Phosphorylation	-	34.82	23927012
191	Phosphorylation	SDFSDLNTQTNWTKS CCCHHCCCCCCCCCC	44.03	30576142
193	Phosphorylation	FSDLNTQTNWTKSLP CHHCCCCCCCCCCCC	30.59	30576142
193 (in isoform 2)	Phosphorylation	-	30.59	25394399
194 (in isoform 2)	Phosphorylation	-	34.30	28152594
196	Phosphorylation	LNTQTNWTKSLPLPT CCCCCCCCCCCCCCC	16.90	30576142
196 (in isoform 2)	Phosphorylation	-	16.90	28152594
198	Phosphorylation	TQTNWTKSLPLPTPE CCCCCCCCCCCCCHH	28.04	30266825
203	Phosphorylation	TKSLPLPTPEEKMRQ CCCCCCCCHHHHHHH	51.52	30266825
209 (in isoform 2)	Phosphorylation	-	36.21	30266825
211 (in isoform 2)	Phosphorylation	-	25.68	30266825
214	Phosphorylation	KMRQQAQTVQADVVP HHHHHHHHCCCCEEE	20.01	27251789
225	Phosphorylation	DVVPINITASGTGQD CEEEEEEEECCCCCC	15.41	29978859
227	Phosphorylation	VPINITASGTGQDDA EEEEEEECCCCCCCC	28.39	29978859
229	Phosphorylation	INITASGTGQDDADG EEEEECCCCCCCCCC	29.22	29978859
236 (in isoform 2)	Phosphorylation	-	19.38	26471730
237 (in isoform 2)	Phosphorylation	-	18.03	28348404
238	Phosphorylation	QDDADGHSVYTPDHY CCCCCCCCCCCCCHH	23.50	29978859
240	Phosphorylation	DADGHSVYTPDHYST CCCCCCCCCCCHHHC	18.64	29978859
241	Phosphorylation	ADGHSVYTPDHYSTL CCCCCCCCCCHHHCC	21.78	29978859
241 (in isoform 2)	Phosphorylation	-	21.78	26471730
242 (in isoform 2)	Phosphorylation	-	14.54	26471730
243 (in isoform 2)	Phosphorylation	-	45.62	26471730
245	Phosphorylation	SVYTPDHYSTLGRFN CCCCCCHHHCCCHHH	15.67	29978859
246	Phosphorylation	VYTPDHYSTLGRFNS CCCCCHHHCCCHHHC	17.46	25849741
247	Phosphorylation	YTPDHYSTLGRFNSC CCCCHHHCCCHHHCC	26.51	29978859
253	Phosphorylation	STLGRFNSCRSAGQR HCCCHHHCCCCCCCC	14.27	24719451
256	Phosphorylation	GRFNSCRSAGQRSET CHHHCCCCCCCCCCC	40.87	24905233
261	Phosphorylation	CRSAGQRSETRDSSC CCCCCCCCCCCCCCC	35.12	24905233
263	Phosphorylation	SAGQRSETRDSSCQT CCCCCCCCCCCCCCC	40.81	24905233
299	Phosphorylation	AAQMGHFSGSSGNMS HHHCCCCCCCCCCCC	31.90	25850435
301	Phosphorylation	QMGHFSGSSGNMSVL HCCCCCCCCCCCCEE	33.60	25850435
302	Phosphorylation	MGHFSGSSGNMSVLS CCCCCCCCCCCCEEE	37.40	22210691
306	Phosphorylation	SGSSGNMSVLSDSAG CCCCCCCCEEECCCC	24.73	25850435
311	Phosphorylation	NMSVLSDSAGIVFPS CCCEEECCCCEECCC	25.64	22210691
319	Methylation	AGIVFPSRLDSDAGF CCEECCCCCCCCCCC	42.63	30760489
322	Phosphorylation	VFPSRLDSDAGFHSL ECCCCCCCCCCCCCC	33.67	30266825
324	Phosphorylation	PSRLDSDAGFHSLPR CCCCCCCCCCCCCCC	26.88	32142685
328	Phosphorylation	DSDAGFHSLPRSGAR CCCCCCCCCCCCCCC	37.50	30266825
357	Phosphorylation	PAGDMNGTFLYQRGH CCCCCCCCEEEECCC	12.88	21945579
360	Phosphorylation	DMNGTFLYQRGHPQA CCCCCEEEECCCCCC	7.62	21945579
378	Phosphorylation	LGHLGGASGTGTLLR CCCCCCCCCCCCCCC	39.91	29255136
380	Phosphorylation	HLGGASGTGTLLRPK CCCCCCCCCCCCCCC	25.21	29255136
382	Phosphorylation	GGASGTGTLLRPKSQ CCCCCCCCCCCCCCC	23.58	29255136
388	Phosphorylation	GTLLRPKSQELRHFE CCCCCCCCCCCCCCC	31.41	27422710
421	Phosphorylation	TSIIPNATLSSSSEV CCCCCCCCCCCCCCE	33.54	28348404
423	Phosphorylation	IIPNATLSSSSEVIA CCCCCCCCCCCCEEE	24.66	28348404
424	Phosphorylation	IPNATLSSSSEVIAI CCCCCCCCCCCEEEE	40.78	28348404
425	Phosphorylation	PNATLSSSSEVIAIP CCCCCCCCCCEEEEE	27.43	28348404
426	Phosphorylation	NATLSSSSEVIAIPT CCCCCCCCCEEEEEC	37.52	28348404
454	Phosphorylation	SSHARIKSRDHLISR CCCCHHHCCHHCHHH	40.34	27251275
470	Phosphorylation	AVKGDPQSPGRHWNE HCCCCCCCCCCCCCC	34.41	29255136
481	Phosphorylation	HWNEGHATILSQDLD CCCCCCCEEECCCCC	19.44	28348404
491	Phosphorylation	SQDLDPHSPGEPALL CCCCCCCCCCCHHHH	39.73	28348404
541	Phosphorylation	PQDVDGKSESSYSGG CCCCCCCCCCCCCCC	48.52	28348404
543	Phosphorylation	DVDGKSESSYSGGGG CCCCCCCCCCCCCCC	41.49	28348404
544	Phosphorylation	VDGKSESSYSGGGGH CCCCCCCCCCCCCCC	21.19	28348404
546	Phosphorylation	GKSESSYSGGGGHSS CCCCCCCCCCCCCCC	32.67	28348404
559	Phosphorylation	SSSEPWEYKSSGNGR CCCCCCCCCCCCCCC	16.58	-
561	Phosphorylation	SEPWEYKSSGNGRAS CCCCCCCCCCCCCCC	42.44	23898821
568	Phosphorylation	SSGNGRASPLKPHLA CCCCCCCCCCCCCCC	29.42	26657352
576	Phosphorylation	PLKPHLATPGYSTPT CCCCCCCCCCCCCCC	24.49	21945579
579	Phosphorylation	PHLATPGYSTPTSNM CCCCCCCCCCCCCCC	15.58	21945579
580	Phosphorylation	HLATPGYSTPTSNMS CCCCCCCCCCCCCCC	33.55	21945579
581	Phosphorylation	LATPGYSTPTSNMSS CCCCCCCCCCCCCCC	23.31	21945579
583	Phosphorylation	TPGYSTPTSNMSSCS CCCCCCCCCCCCCCC	32.59	21945579
584	Phosphorylation	PGYSTPTSNMSSCSL CCCCCCCCCCCCCCC	31.57	21945579
587	Phosphorylation	STPTSNMSSCSLDQT CCCCCCCCCCCCCCC	32.23	21945579
588	Phosphorylation	TPTSNMSSCSLDQTS CCCCCCCCCCCCCCC	9.28	21945579
590	Phosphorylation	TSNMSSCSLDQTSNK CCCCCCCCCCCCCCC	36.61	21945579
639	Phosphorylation	GFGNPRHSVINVFVG CCCCCCHHEEEEEEE	26.44	25159151
656	Phosphorylation	QKNQGDRSNYQDKSL HCCCCCCCCCCCHHH	44.63	23312004
658	Phosphorylation	NQGDRSNYQDKSLSR CCCCCCCCCCHHHHH	21.23	25002506
662	Phosphorylation	RSNYQDKSLSRNISL CCCCCCHHHHHCCCC	39.61	25849741
664	Phosphorylation	NYQDKSLSRNISLKK CCCCHHHHHCCCCCC	30.30	25002506
668	Phosphorylation	KSLSRNISLKKAKKP HHHHHCCCCCCCCCC	37.37	29496963
682	Phosphorylation	PPLPPSRTDSLRRIP CCCCCCCCHHHHCCC	33.99	27282143
684	Phosphorylation	LPPSRTDSLRRIPKK CCCCCCHHHHCCCCC	24.14	20068231
692	Phosphorylation	LRRIPKKSSQCNGQV HHCCCCCCCCCCCHH	31.59	24719451
720	Phosphorylation	QLSLPGKSGSSPSQS HHCCCCCCCCCCCCC	50.23	25159151
722	Phosphorylation	SLPGKSGSSPSQSPC CCCCCCCCCCCCCCC	46.28	25159151
723	Phosphorylation	LPGKSGSSPSQSPCS CCCCCCCCCCCCCCC	31.90	23927012
725	Phosphorylation	GKSGSSPSQSPCSDL CCCCCCCCCCCCCCC	45.28	23927012
727	Phosphorylation	SGSSPSQSPCSDLEE CCCCCCCCCCCCCCC	32.01	23927012
730	Phosphorylation	SPSQSPCSDLEEPWL CCCCCCCCCCCCCCC	48.92	22777824
740	Phosphorylation	EEPWLPRSRSQSTVS CCCCCCCCCCCCCCC	34.05	23312004
742	Phosphorylation	PWLPRSRSQSTVSAG CCCCCCCCCCCCCCC	29.72	24719451
744	Phosphorylation	LPRSRSQSTVSAGSS CCCCCCCCCCCCCCC	31.83	28348404
745	Phosphorylation	PRSRSQSTVSAGSSM CCCCCCCCCCCCCCC	15.73	30576142
747	Phosphorylation	SRSQSTVSAGSSMTS CCCCCCCCCCCCCCC	27.31	28348404
756	Phosphorylation	GSSMTSATTPNVYSL CCCCCCCCCCCCHHC	42.42	24719451
762	Phosphorylation	ATTPNVYSLCGATPS CCCCCCHHCCCCCCC	16.95	-
769	Phosphorylation	SLCGATPSQSDTSSV HCCCCCCCCCCCCCC	37.65	30576142
771	Phosphorylation	CGATPSQSDTSSVKS CCCCCCCCCCCCCCC	47.39	-
773	Phosphorylation	ATPSQSDTSSVKSEY CCCCCCCCCCCCCCC	28.31	-
827	Phosphorylation	VQEGSRATMPQVPGG CCCCCCCCCCCCCCC	28.42	30576142
835	Phosphorylation	MPQVPGGSVKPKIMS CCCCCCCCCCCCCCC	32.65	28555341
842	Phosphorylation	SVKPKIMSPEKSHRV CCCCCCCCCCCCCEE	33.12	27422710
846	Phosphorylation	KIMSPEKSHRVISPS CCCCCCCCCEEECCC	18.18	23312004
851	Phosphorylation	EKSHRVISPSSGYSS CCCCEEECCCCCCCC	18.84	21945579
853	Phosphorylation	SHRVISPSSGYSSQS CCEEECCCCCCCCCC	29.60	21945579
854	Phosphorylation	HRVISPSSGYSSQSN CEEECCCCCCCCCCC	45.17	21945579
856	Phosphorylation	VISPSSGYSSQSNTP EECCCCCCCCCCCCC	13.70	21945579
857	Phosphorylation	ISPSSGYSSQSNTPT ECCCCCCCCCCCCCC	25.98	21945579
858	Phosphorylation	SPSSGYSSQSNTPTA CCCCCCCCCCCCCCC	29.19	21945579
860	Phosphorylation	SSGYSSQSNTPTALT CCCCCCCCCCCCCCC	44.62	21945579
862	Phosphorylation	GYSSQSNTPTALTPV CCCCCCCCCCCCCCC	27.54	21945579
864	Phosphorylation	SSQSNTPTALTPVPV CCCCCCCCCCCCCCE	32.06	21945579
867	Phosphorylation	SNTPTALTPVPVFLK CCCCCCCCCCCEEEE	21.56	21945579
877	Phosphorylation	PVFLKSVSPANGKGK CEEEECCCCCCCCCC	25.94	24719451
894	Phosphorylation	PKVPERKSSLISSVS CCCCCCHHHCEEEEE	36.28	30576142
895	Phosphorylation	KVPERKSSLISSVSI CCCCCHHHCEEEEEE	32.53	27251275
898	Phosphorylation	ERKSSLISSVSISSS CCHHHCEEEEEEECC	29.95	-
901	Phosphorylation	SSLISSVSISSSSTS HHCEEEEEEECCCCC	20.78	30576142
910	Phosphorylation	SSSSTSLSSSTSTEG ECCCCCCCCCCCCCC	23.24	30576142
911	Phosphorylation	SSSTSLSSSTSTEGS CCCCCCCCCCCCCCC	42.82	-
912	Phosphorylation	SSTSLSSSTSTEGSG CCCCCCCCCCCCCCC	24.01	30576142
914	Phosphorylation	TSLSSSTSTEGSGTM CCCCCCCCCCCCCCC	26.80	-
915	Phosphorylation	SLSSSTSTEGSGTMK CCCCCCCCCCCCCCC	44.44	-
918	Phosphorylation	SSTSTEGSGTMKKLD CCCCCCCCCCCCCCC	25.51	30576142
930	Phosphorylation	KLDPAVGSPPAPPPP CCCCCCCCCCCCCCC	22.55	29255136
941	Phosphorylation	PPPPPVPSPPFPCPA CCCCCCCCCCCCCCC	45.50	29255136
995	Phosphorylation	SPPDWCLSPPRPALS CCCCCCCCCCCCCCC	29.71	24719451
1043	Phosphorylation	KDTRPPFTNSGQPES CCCCCCCCCCCCCCC	33.96	21406692
1045	Phosphorylation	TRPPFTNSGQPESSR CCCCCCCCCCCCCCC	35.43	21406692
1050	Phosphorylation	TNSGQPESSRGSLRP CCCCCCCCCCCCCCC	31.83	21406692
1051	Phosphorylation	NSGQPESSRGSLRPP CCCCCCCCCCCCCCC	38.71	21406692
1054	Phosphorylation	QPESSRGSLRPPSTK CCCCCCCCCCCCCCC	21.79	21406692
1059	Phosphorylation	RGSLRPPSTKEETSR CCCCCCCCCCCCCCC	55.59	21406692
1060	Phosphorylation	GSLRPPSTKEETSRP CCCCCCCCCCCCCCC	48.53	21406692
1065	Phosphorylation	PSTKEETSRPPMPLI CCCCCCCCCCCCCCE	46.17	22210691
1073	Phosphorylation	RPPMPLITTEALQMV CCCCCCEEHHHHHHH	26.68	22210691
1089	Phosphorylation	LRPVRKNSGAEAAQL CCCCCCCCHHHHHHH	42.27	29255136
1097	Phosphorylation	GAEAAQLSERTAQEQ HHHHHHHHHHHHHHH	16.98	23403867
1106	Phosphorylation	RTAQEQRTPVAPQYH HHHHHHCCCCCCCCC	23.08	25159151
1112	Phosphorylation	RTPVAPQYHLKPSAF CCCCCCCCCCCHHHH	14.20	-
1115	Acetylation	VAPQYHLKPSAFLKS CCCCCCCCHHHHHHC	24.50	26051181
1122	Phosphorylation	KPSAFLKSRNSTNEM CHHHHHHCCCCCCCC	38.55	28555341
1125	Phosphorylation	AFLKSRNSTNEMESE HHHHCCCCCCCCCCC	31.34	21406692
1126	Phosphorylation	FLKSRNSTNEMESES HHHCCCCCCCCCCCC	38.45	21406692
1131	Phosphorylation	NSTNEMESESQPASV CCCCCCCCCCCCCCC	41.04	21406692
1133	Phosphorylation	TNEMESESQPASVTS CCCCCCCCCCCCCCC	51.23	21406692
1137	Phosphorylation	ESESQPASVTSSLPT CCCCCCCCCCCCCCC	32.39	21406692
1139	Phosphorylation	ESQPASVTSSLPTPA CCCCCCCCCCCCCCC	15.31	21406692
1140	Phosphorylation	SQPASVTSSLPTPAK CCCCCCCCCCCCCCC	27.93	21406692
1141	Phosphorylation	QPASVTSSLPTPAKS CCCCCCCCCCCCCCC	29.06	21406692
1144	Phosphorylation	SVTSSLPTPAKSSSQ CCCCCCCCCCCCCCC	40.97	25850435
1165	Phosphorylation	AERGGPVSRSPGAPS HHHCCCCCCCCCCCC	30.12	23312004
1167	Phosphorylation	RGGPVSRSPGAPSAG HCCCCCCCCCCCCCC	21.85	29255136
1172	Phosphorylation	SRSPGAPSAGEAEAR CCCCCCCCCCCCCCC	48.66	29255136
1181	Phosphorylation	GEAEARPSPSTTPLP CCCCCCCCCCCCCCC	26.40	29255136
1183	Phosphorylation	AEARPSPSTTPLPDS CCCCCCCCCCCCCCC	49.61	29255136
1184	Phosphorylation	EARPSPSTTPLPDSS CCCCCCCCCCCCCCC	35.50	29255136
1185	Phosphorylation	ARPSPSTTPLPDSSP CCCCCCCCCCCCCCC	27.45	29255136
1190	Phosphorylation	STTPLPDSSPSRKPP CCCCCCCCCCCCCCC	42.06	29255136
1191	Phosphorylation	TTPLPDSSPSRKPPP CCCCCCCCCCCCCCC	33.98	29255136
1193	Phosphorylation	PLPDSSPSRKPPPIS CCCCCCCCCCCCCCC	55.68	29255136
1233	Phosphorylation	EALRAVPSPTTGEEG HHHHCCCCCCCCCCC	28.42	29255136
1235	Phosphorylation	LRAVPSPTTGEEGSV HHCCCCCCCCCCCCC	52.34	25159151
1236	Phosphorylation	RAVPSPTTGEEGSVH HCCCCCCCCCCCCCC	46.08	23927012
1241	Phosphorylation	PTTGEEGSVHSREAK CCCCCCCCCCCHHHH	21.67	23403867
1244	Phosphorylation	GEEGSVHSREAKESS CCCCCCCCHHHHHCH	29.66	23403867
1250	Phosphorylation	HSREAKESSAAQAGS CCHHHHHCHHHHCCC	25.27	29255136
1251	Phosphorylation	SREAKESSAAQAGSH CHHHHHCHHHHCCCC	28.81	29255136
1257	Phosphorylation	SSAAQAGSHATHPGT CHHHHCCCCCCCCCC	16.99	25022875
1260	Phosphorylation	AQAGSHATHPGTSVL HHCCCCCCCCCCCCC	24.15	25022875
1264	Phosphorylation	SHATHPGTSVLEGGA CCCCCCCCCCCCCCC	21.80	25002506
1265	Phosphorylation	HATHPGTSVLEGGAA CCCCCCCCCCCCCCC	30.53	22912867
1274	Phosphorylation	LEGGAAGSMSPSRVE CCCCCCCCCCHHHHC	16.03	29255136
1276	Phosphorylation	GGAAGSMSPSRVEAN CCCCCCCCHHHHCCC	22.78	29255136
1278	Phosphorylation	AAGSMSPSRVEANVP CCCCCCHHHHCCCCC	41.47	29255136
1292	Phosphorylation	PMVQPDVSPAPKQEE CCCCCCCCCCCCCCC	23.79	29255136
1350	Phosphorylation	DGNDEVMTPSRPRTT CCCCCCCCCCCCCCH	24.24	29255136
1352	Phosphorylation	NDEVMTPSRPRTTED CCCCCCCCCCCCHHH	45.83	29255136
1356	O-linked_Glycosylation	MTPSRPRTTEDLFAA CCCCCCCCHHHHHHH	36.90	30379171
1357	O-linked_Glycosylation	TPSRPRTTEDLFAAI CCCCCCCHHHHHHHH	28.87	30379171
1367	O-linked_Glycosylation	LFAAIHRSKRKVLGR HHHHHHHHHCHHCCC	23.73	30379171
1367	Phosphorylation	LFAAIHRSKRKVLGR HHHHHHHHHCHHCCC	23.73	25056879
1377	Phosphorylation	KVLGRRDSDDDHSRN HHCCCCCCCCCCCCC	40.92	20873877
1382	Phosphorylation	RDSDDDHSRNHSPSP CCCCCCCCCCCCCCC	41.60	20873877
1384	Phosphorylation	SDDDHSRNHSPSPPV CCCCCCCCCCCCCCC	42.90	33259812
1386	Phosphorylation	DDHSRNHSPSPPVTP CCCCCCCCCCCCCCC	30.53	29255136
1388	Phosphorylation	HSRNHSPSPPVTPTG CCCCCCCCCCCCCCC	44.87	29255136
1392	Phosphorylation	HSPSPPVTPTGAAPS CCCCCCCCCCCCCCC	22.40	29255136
1394	Phosphorylation	PSPPVTPTGAAPSLA CCCCCCCCCCCCCCC	30.04	29255136
1399	Phosphorylation	TPTGAAPSLASPKQV CCCCCCCCCCCHHHH	31.66	25849741
1402	Phosphorylation	GAAPSLASPKQVGSI CCCCCCCCHHHHHHH	37.61	23927012
1408	Phosphorylation	ASPKQVGSIQRSIRK CCHHHHHHHHHHHHC	19.38	-
1412	Phosphorylation	QVGSIQRSIRKSSTS HHHHHHHHHHCCCCC	15.46	26546556
1415	Methylation	SIQRSIRKSSTSSDN HHHHHHHCCCCCCHH	47.27	115973995
1416	Phosphorylation	IQRSIRKSSTSSDNF HHHHHHCCCCCCHHH	29.06	24719451
1417	Phosphorylation	QRSIRKSSTSSDNFK HHHHHCCCCCCHHHH	35.03	28674419
1424	Methylation	STSSDNFKALLLKKG CCCCHHHHHHHHHCC	44.36	115974003
1434	Phosphorylation	LLKKGSRSDTSARMS HHHCCCCCCHHHHHH	47.11	20068231
1436	Phosphorylation	KKGSRSDTSARMSAA HCCCCCCHHHHHHHH	26.07	20068231
1437	Phosphorylation	KGSRSDTSARMSAAE CCCCCCHHHHHHHHH	20.90	20068231
1441	Phosphorylation	SDTSARMSAAEMLKN CCHHHHHHHHHHHHC	20.83	23312004
1456	Phosphorylation	TDPRFQRSRSEPSPD CCHHHHHCCCCCCCC	29.40	23403867
1458	Phosphorylation	PRFQRSRSEPSPDAP HHHHHCCCCCCCCCC	55.92	23403867
1461	Phosphorylation	QRSRSEPSPDAPESP HHCCCCCCCCCCCCC	31.21	23403867
1467	Phosphorylation	PSPDAPESPSSCSPS CCCCCCCCCCCCCCC	29.08	25159151
1469	Phosphorylation	PDAPESPSSCSPSKN CCCCCCCCCCCCCCC	53.94	25159151
1470	Phosphorylation	DAPESPSSCSPSKNR CCCCCCCCCCCCCCH	23.23	25849741
1472	Phosphorylation	PESPSSCSPSKNRRA CCCCCCCCCCCCHHH	33.87	25159151
1474	Phosphorylation	SPSSCSPSKNRRAQE CCCCCCCCCCHHHHH	26.69	25159151
1493	Phosphorylation	NEGLMPRSLSFSGPR HCCCCCCCCCCCCCC	23.61	23403867
1495	Phosphorylation	GLMPRSLSFSGPRYG CCCCCCCCCCCCCCC	20.72	28355574
1497	Phosphorylation	MPRSLSFSGPRYGRS CCCCCCCCCCCCCCC	44.50	23403867
1504	Phosphorylation	SGPRYGRSRTPPSAA CCCCCCCCCCCCCHH	35.82	29396449
1506	Phosphorylation	PRYGRSRTPPSAASS CCCCCCCCCCCHHHH	40.58	29396449
1509	Phosphorylation	GRSRTPPSAASSRYS CCCCCCCCHHHHHHH	37.36	22199227
1512	Phosphorylation	RTPPSAASSRYSMRN CCCCCHHHHHHHHHH	18.31	24719451
1513	Phosphorylation	TPPSAASSRYSMRNR CCCCHHHHHHHHHHH	30.43	22199227
1516	Phosphorylation	SAASSRYSMRNRIQS CHHHHHHHHHHHHHC	15.34	24961811
1523	Phosphorylation	SMRNRIQSSPMTVIS HHHHHHHCCCCEEEE	33.75	28348404
1524	Phosphorylation	MRNRIQSSPMTVISE HHHHHHCCCCEEEEC	11.43	27050516
1527	Phosphorylation	RIQSSPMTVISEGEG HHHCCCCEEEECCCC	20.33	28348404
1530	Phosphorylation	SSPMTVISEGEGEAV CCCCEEEECCCCCCC	34.90	27050516
1555	Phosphorylation	LGAAEGCSLDGLARE HHHHCCCCCCCCCCC	40.11	25850435
1599	Phosphorylation	SAEGREPSPQCGGSL CCCCCCCCCCCCCCC	23.89	28985074
1605	Phosphorylation	PSPQCGGSLSEES-- CCCCCCCCCCCCC--	17.63	26471730
1607	Phosphorylation	PQCGGSLSEES---- CCCCCCCCCCC----	40.80	-
1610	Phosphorylation	GGSLSEES------- CCCCCCCC-------	41.28	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of NHSL1_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NHSL1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NHSL1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of NHSL1_HUMAN !!

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NHSL1_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1472, AND MASSSPECTROMETRY.	19413330 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1386; SER-1388 ANDTHR-1392, AND MASS SPECTROMETRY.	18669648 [Abstract]
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis."; Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III; J. Proteome Res. 7:1346-1351(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1190; SER-1191;SER-1193; SER-1233; SER-1276 AND SER-1278, AND MASS SPECTROMETRY.	18220336 [Abstract]