NGN1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NGN1_MOUSE
• UniProt AC: P70660
• Protein Name: Neurogenin-1
• Gene Name: Neurog1
• Organism: Mus musculus (Mouse).
• Sequence Length: 244
• Subcellular Localization: Nucleus .
• Protein Description: Acts as a transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis..
• Protein Sequence: MPAPLETCISDLDCSSSNSSSDLSSFLTDEEDCARLQPLASTSGLSVPARRSAPALSGASNVPGAQDEEQERRRRRGRARVRSEALLHSLRRSRRVKANDRERNRMHNLNAALDALRSVLPSFPDDTKLTKIETLRFAYNYIWALAETLRLADQGLPGGSARERLLPPQCVPCLPGPPSPASDTESWGSGAAASPCATVASPLSDPSSPSASEDFTYGPGDPLFSFPGLPKDLLHTTPCFIPYH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
130	Phosphorylation	FPDDTKLTKIETLRF CCCCCCCCCHHHHHH	31.37	17623011

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NGN1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NGN1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NGN1_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of NGN1_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.