dbPTM

NFD5_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NFD5_ARATH
UniProt AC	Q8LEZ4
Protein Name	Protein NUCLEAR FUSION DEFECTIVE 5, mitochondrial {ECO:0000303\|PubMed:16698901}
Gene Name	NFD5 {ECO:0000303\|PubMed:16698901}
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	372
Subcellular Localization	Mitochondrion .
Protein Description	Required for karyogamy during female gametophyte development, when the two polar nuclei fuse to form the diploid central cell nucleus..
Protein Sequence	MKSFLLSRQAIHRISLLSSKTPTFCRNFSAITSTISHSDRHLRSYDEQTPFQNVEIPRPISSFNRYFHFTRESRLSESSAAIDDSNDQEEDDEDGTTNEFLSRFVWIMRGKVSEAYPDCDKKMIDGMLLLIVEKVVEEIERGGFNKVGSAPPSPSSEFSDDLWATIWEVSNTVLKDMEKERKKEKMKQYVQSPEVMEMCRFAGEIGIRGDLLRELRFKWAREKMDDAEFYESLEQQRDLDNSIRESETVDGEVEEEGFVPSDEVESRSISLPKRKGKLKYKIYGLELSDPKWVEMADKIHEAEEEADWREPKPVTGKCKLVMEKLESLQEGDDPSGLLAEWAELLEPNRVDWIALINQLREGNTHAYLKVRL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
261	Phosphorylation	EEEGFVPSDEVESRS CCCCCCCHHHHCCCC	40.89	30407730
266	Phosphorylation	VPSDEVESRSISLPK CCHHHHCCCCCCCCC	36.18	30407730
283	Phosphorylation	GKLKYKIYGLELSDP CCCCEEEEEEECCCH	16.11	28295753

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of NFD5_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NFD5_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NFD5_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of NFD5_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NFD5_ARATH

Related Literatures of Post-Translational Modification