NETA_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NETA_DROME
• UniProt AC: Q24567
• Protein Name: Netrin-A
• Gene Name: NetA
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 726
• Subcellular Localization: Secreted, extracellular space, extracellular matrix.
• Protein Description: Netrins control guidance of CNS commissural axons at the midline and peripheral motor axons to their target muscles..
• Protein Sequence: MIRGILLLLLGTTRFSPIQCISNDVYFKMFSQQAPPEDPCYNKAHEPRACIPDFVNAAYDAPVVASSTCGSSGAQRYCEYQDHERSCHTCDMTDPLRSFPARSLTDLNNSNNVTCWRSEPVTGSGDNVTLTLSLGKKFELTYVILQLCPHAPRPDSMVIYKSTDHGLSWQPFQFFSSQCRRLFGRPARQSTGRHNEHEARCSDVTRPLVSRIAFSTLEGRPSSRDLDSSPVLQDWVTATDIRVVFHRLQRPDPQALLSLEAGGATDLASGKYSVPLANGPAGNNIEANLGGDVATSGSGLHYAISDFSVGGRCKCNGHASKCSTDASGQLNCECSHNTAGRDCERCKPFHFDRPWARATAKEANECKECNCNKHARQCRFNMEIFRLSQGVSGGVCQNCRHSTTGRNCHQCKEGFYRDATKPLTHRKVCKACDCHPIGSSGKICNSTSGQCPCKDGVTGLTCNRCARGYQQSRSHIAPCIKQPPRMINMLDTQNTAPEPDEPESSPGSGGDRNGAAGMAAQSQYYRTEGGRECGKCRVSTKRLNLNKFCKRDYAIMAKVIGRDTSSEAVSREVQRRAMDPDVADYEMDQVQPGSARSPITGVYEFQAADYPNPNPNPRGSEMERFDLQIQAVFKRSRPGESSGAGNVYGMPNTTLKRGPMTWIIPTKDLECRCPRIRVNRSYLILGRDSEAPPGYLGIGPHSIVIEWKEDWYRRMKRFQRRARTCA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
108	N-linked_Glycosylation	ARSLTDLNNSNNVTC CCCCCCCCCCCCCEE	53.33	-
112	N-linked_Glycosylation	TDLNNSNNVTCWRSE CCCCCCCCCEEEECC	30.23	-
127	N-linked_Glycosylation	PVTGSGDNVTLTLSL CCCCCCCEEEEEEEC	32.00	-
445	N-linked_Glycosylation	GSSGKICNSTSGQCP CCCCCCCCCCCCCCC	52.36	-
522	Phosphorylation	AAGMAAQSQYYRTEG CCCHHHHCCEEECCC	18.54	30478224
652	N-linked_Glycosylation	GNVYGMPNTTLKRGP CCCCCCCCCCCCCCC	36.48	-
679	N-linked_Glycosylation	RCPRIRVNRSYLILG CCCCEEECCCEEEEE	19.82	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NETA_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NETA_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NETA_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SEM2A_DROME	Sema-2a	genetic	9604933

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.