NET3_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NET3_MOUSE
• UniProt AC: Q9R1A3
• Protein Name: Netrin-3
• Gene Name: Ntn3
• Organism: Mus musculus (Mouse).
• Sequence Length: 580
• Subcellular Localization: Secreted, extracellular space, extracellular matrix .
• Protein Description: Netrins control guidance of CNS commissural axons and peripheral motor axons..
• Protein Sequence: MPTWLWGLLLTAGTLSAALSPGLPASADPCYDEAREPRSCIPGLVNAALGREVLASSTCGRSANRVCDSSDPQRAHSADLLTSAPGTASPLCWRSDLLQQAPFNVTLTVPLGKAFELVFVSLRFCSAPPTSVALLKSQDHGRSWVPLGFFSSSCTLDYGRLPAPADGPSGPGPEALCFPAPQAQPDGGGLLAFSVQDGSPQGLDLDNSPVLQDWVTATDIRIVLTRPAIQGDTRDGGVTVPYSYSATELQVGGRCKCNGHASRCLLDTHGHLVCDCQHGTEGPDCSRCKPFYCDRPWQRATGQEAHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRVLSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVAPCVKTPVPGPTEESSPVEPQDCESHCRPARGSYRISLKKFCRKDYAVQVAVGARGEARGSWTRFPVAVLAVFRSGEERARRGSSALWVPTLDAACGCPRLLPGRRYLLLGGGPGAAAGSTAGRGQGLSAARGSLVLPWRDAWTRRLRRLQRRERRGRCGTA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
56	Phosphorylation	LGREVLASSTCGRSA HCCHHHHHCCCCCCC	23.24	29899451
62	Phosphorylation	ASSTCGRSANRVCDS HHCCCCCCCCCCCCC	18.38	29899451
104	N-linked_Glycosylation	LLQQAPFNVTLTVPL HHHHCCCEEEEEEEC	25.46	-
152	Phosphorylation	VPLGFFSSSCTLDYG EEEEEECCCCEEECC	25.03	-
155	Phosphorylation	GFFSSSCTLDYGRLP EEECCCCEEECCCCC	25.31	-
387	N-linked_Glycosylation	GAAGKTCNQTTGQCP CCCCCCCCCCCCCCC	47.68	-
525	Phosphorylation	RLLPGRRYLLLGGGP CCCCCCEEEEECCCC	10.59	24719451
539	Phosphorylation	PGAAAGSTAGRGQGL CCCCCCCCCCCCCCC	32.01	24719451
562	Phosphorylation	LPWRDAWTRRLRRLQ EEHHHHHHHHHHHHH	13.97	28059163

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NET3_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NET3_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NET3_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of NET3_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.