dbPTM

NEMP2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NEMP2_HUMAN
UniProt AC	A6NFY4
Protein Name	Nuclear envelope integral membrane protein 2
Gene Name	NEMP2
Organism	Homo sapiens (Human).
Sequence Length	417
Subcellular Localization	Nucleus inner membrane Multi-pass membrane protein Nucleoplasmic side .
Protein Description
Protein Sequence	MGPRQGRWWLLLWLPPLATLPVRGEAAAAALSVRRCKALKEKDLIRTSESDCYCYNQNSQVEWKYIWSTMQVKITSPGLFRIVYIAERHNCQYPENILSFIKCVIHNFWIPKESNEITIIINPYRETVCFSVEPVKKIFNYMIHVNRNIMDFKLFLVFVAGVFLFFYARTLSQSPTFYYSSGTVLGVLMTLVFVLLLVKRFIPKYSTFWALMVGCWFASVYIVCQLMEDLKWLWYENRIYVLGYVLIVGFFSFVVCYKHGPLADDRSRSLLMWMLRLLSLVLVYAGVAVPQFAYAAIILLMSSWSLHYPLRACSYMRWKMEQWFTSKELVVKYLTEDEYREQADAETNSALEELRRACRKPDFPSWLVVSRLHTPSKFADFVLGGSHLSPEEISLHEEQYGLGGAFLEEQLFNPSTA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
32	Phosphorylation	EAAAAALSVRRCKAL HHHHHHHHHHHHHHH	-
99	Phosphorylation	QYPENILSFIKCVIH CCCHHHHHHHHHHHH	24719451
124	Phosphorylation	ITIIINPYRETVCFS EEEEECCCCCCEEEE	-
167	Phosphorylation	AGVFLFFYARTLSQS HHHHHHHHHHHHCCC	-
332	Ubiquitination	TSKELVVKYLTEDEY CCHHHHHHHHCHHHH	29967540
360	Ubiquitination	ELRRACRKPDFPSWL HHHHHHCCCCCCCEE	-
370	Phosphorylation	FPSWLVVSRLHTPSK CCCEEEEECCCCCCH	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of NEMP2_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NEMP2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NEMP2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of NEMP2_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NEMP2_HUMAN

Related Literatures of Post-Translational Modification