NEK6_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NEK6_ARATH
• UniProt AC: Q9LT35
• Protein Name: Serine/threonine-protein kinase Nek6
• Gene Name: NEK6
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 416
• Protein Description: May be involved in plant development processes..
• Protein Sequence: MDDYEVVEQIGRGAFGSAFLVIHKSERRKYVVKKIRLAKQTERCKLAAIQEMSLISKLKSPYIVEYKDSWVEKDCVCIVTSYCEGGDMTQMIKKSRGVFASEEKLCRWMVQLLLAIDYLHNNRVLHRDLKCSNIFLTKENEVRLGDFGLAKLLGKDDLASSMVGTPNYMCPELLADIPYGYKSDIWSLGCCMFEVAAHQPAFKAPDMAALINKINRSSLSPLPVMYSSSLKRLIKSMLRKNPEHRPTAAELLRHPHLQPYLAQCQNLSPVFKPVVSKSEHNTNENRTGLPPKTKSAKTPIKHNQESEETEKKNKDTSSSSKDKERPAKSQEMSVISTLTLLREFQKKSPKSEERAEALESLLELCAGLLRQEKFDELEGVLKPFGDETVSSRETAIWLTKSLMNVKRKQNDDETNI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
56	Phosphorylation	IQEMSLISKLKSPYI HHHHHHHHHCCCCEE	36.91	19880383
329	Phosphorylation	DKERPAKSQEMSVIS CCCCCCHHHHHHHHH	33.22	30407730
333	Phosphorylation	PAKSQEMSVISTLTL CCHHHHHHHHHHHHH	18.62	30407730
336	Phosphorylation	SQEMSVISTLTLLRE HHHHHHHHHHHHHHH	18.40	30407730
337	Phosphorylation	QEMSVISTLTLLREF HHHHHHHHHHHHHHH	16.79	30407730
339	Phosphorylation	MSVISTLTLLREFQK HHHHHHHHHHHHHHH	24.68	30407730

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NEK6_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NEK6_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NEK6_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of NEK6_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.