dbPTM

NEK3_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NEK3_ARATH
UniProt AC	Q8RX66
Protein Name	Serine/threonine-protein kinase Nek3
Gene Name	NEK3
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	568
Subcellular Localization
Protein Description	May be involved in plant development processes..
Protein Sequence	MEHYEVLEQIGKGSFGSALLVRHKHEKKLYVLKKIRLARQTGRTRRSAHQEMELISKIRNPFIVEYKDSWVEKGCYVCIVIGYCKGGDMAEAIKKANGVEFSEEKLCKWLVQLLMALEYLHASHILHRDVKCSNIFLTKDQDIRLGDFGLAKILTSDDLASSVVGTPSYMCPELLADIPYGSKSDIWSLGCCMYEMTALKPAFKAFDMQGLINRINRSIVAPLPAQYSTAFRSLVKSMLRKNPELRPSASDLLRQPLLQPYVQKVLLKLSFREHDTLPSESERRSSYPQQRKRTSGKSVSFGPSRFGVDQEDSVSSVKPVHTYLHRHRPVDLSANDTSRVVVRRPAVSSVVSNSSKYVPVRSNQPKSGGLLKPAVVTRRASLPISQKPAKGTKDSLYHPNIGILHQLNSPDVSVNSPRIDRIKFPLASYEEMPFIPVVRKKKGSSRGSYSPPPEPPLDCSITKDKFTLEPERETKSDLSDQNATAGASSRASSGASRRQRFDPSSYRQRAEALEGLLEFSARLLIDERYDELNVLLKPFGPGKVSPRETAIWLSKSFKESSPSNLEED

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MEHYEVLEQIG ----CCHHHHHHHHC	8.40	24243849
14	Phosphorylation	LEQIGKGSFGSALLV HHHHCCCCCCCEEEE	29.89	25561503
17	Phosphorylation	IGKGSFGSALLVRHK HCCCCCCCEEEEECC	17.46	25561503
248	Phosphorylation	KNPELRPSASDLLRQ HCCHHCCCHHHHHHC	33.69	28011693
250	Phosphorylation	PELRPSASDLLRQPL CHHCCCHHHHHHCHH	32.88	28011693

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of NEK3_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NEK3_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NEK3_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of NEK3_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NEK3_ARATH

Related Literatures of Post-Translational Modification