NDUS1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NDUS1_ARATH
• UniProt AC: Q9FGI6
• Protein Name: NADH dehydrogenase [ubiquinone] iron-sulfur protein 1, mitochondrial
• Gene Name: EMB1467
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 748
• Subcellular Localization: Mitochondrion inner membrane. Matrix and cytoplasmic side of the mitochondrial inner membrane..
• Protein Description: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). This is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized (By similarity)..
• Protein Sequence: MGLGILASRTIRPASRLLQSQTSNFFLRTIVSKPELQSPESAAVSEPEPPTQILPPRNPVGGARVHFSNPEDAIEVFVDGYAVKVPKGFTVLQACEVAGVDIPRFCYHSRLSIAGNCRMCLVEVEKSPKPVASCAMPALPGMKIKTDTPIAKKAREGVMEFLLMNHPLDCPICDQGGECDLQDQSMAFGSDRGRFTEMKRSVVDKNLGPLVKTVMTRCIQCTRCVRFASEVAGVQDLGILGRGSGEEIGTYVEKLMTSELSGNVIDICPVGALTSKPFAFKARNWELKATETIDVSDAVGSNIRVDSRGPEVMRIIPRLNEDINEEWISDKTRFCYDGLKRQRLSDPMIRDSDGRFKAVSWRDALAVVGDIIHQVKPDEIVGVAGQLSDAESMMVLKDFVNRMGSDNVWCEGTAAGVDADLRYSYLMNTSISGLENADLFLLIGTQPRVEAAMVNARICKTVRASNAKVGYVGPPAEFNYDCKHLGTGPDTLKEIAEGRHPFCTALKNAKNPAIIVGAGLFNRTDKNAILSSVESIAQANNVVRPDWNGLNFLLQYAAQAAALDLGLIQQSAKALESAKFVYLMGADDVNVDKIPKDAFVVYQGHHGDKAVYRANVILPASAFTEKEGTYENTEGFTQQTVPAVPTVGDARDDWKIVRALSEVSGVKLPYNSIEGVRSRIKSVAPNLVHTDEREPAAFGPSLKPECKEAMSTTPFQTVVENFYMTNSITRASKIMAQCSAVLLKKPFV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
22	Phosphorylation	SRLLQSQTSNFFLRT HHHHHHHCCCCHHHH	30.77	22074104
23	Phosphorylation	RLLQSQTSNFFLRTI HHHHHHCCCCHHHHH	24.81	22074104
394	Sulfoxidation	LSDAESMMVLKDFVN CCCHHHHHHHHHHHH	4.43	23289948
582	Phosphorylation	LESAKFVYLMGADDV HHHCCEEEEECCCCC	8.29	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NDUS1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NDUS1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NDUS1_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of NDUS1_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.