NDUBB_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NDUBB_MOUSE
• UniProt AC: O09111
• Protein Name: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial
• Gene Name: Ndufb11
• Organism: Mus musculus (Mouse).
• Sequence Length: 151
• Subcellular Localization: Mitochondrion inner membrane ; Single-pass membrane protein .
• Protein Description: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone..
• Protein Sequence: MAARLLSLYGRCLSAAGAMRGLPAARVRWESSRAVIAPSGVEKKRQREPTMQWQEDPEPEDENVYAKNPDFHGYDSDPVVDVWNMRAVFFFGFSIVLVFGTTFVAYVPDYRMQEWARREAERLVKYREVNGLPIMESNYFDPSKIQLPEDD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
39	Phosphorylation	SRAVIAPSGVEKKRQ CCEEECCCCCCHHHC	46.58	23140645
43	Acetylation	IAPSGVEKKRQREPT ECCCCCCHHHCCCCC	51.34	23864654
43	Succinylation	IAPSGVEKKRQREPT ECCCCCCHHHCCCCC	51.34	23806337
43	Malonylation	IAPSGVEKKRQREPT ECCCCCCHHHCCCCC	51.34	26320211
126	Phosphorylation	EAERLVKYREVNGLP HHHHHHHHHHHCCEE	12.43	30165576
127	Methylation	AERLVKYREVNGLPI HHHHHHHHHHCCEEC	35.35	4199143
137	Phosphorylation	NGLPIMESNYFDPSK CCEECCCCCCCCHHH	21.32	22210690
139	Phosphorylation	LPIMESNYFDPSKIQ EECCCCCCCCHHHCC	20.73	22210690

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NDUBB_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NDUBB_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NDUBB_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of NDUBB_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.