NDUBA_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NDUBA_MOUSE
• UniProt AC: Q9DCS9
• Protein Name: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10
• Gene Name: Ndufb10
• Organism: Mus musculus (Mouse).
• Sequence Length: 176
• Subcellular Localization: Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side .
• Protein Description: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone..
• Protein Sequence: MPDSWDKDVYPEPPSRTPAPSPQTSLPNPITYLTKAYDLVVDWPVTLVREFIERQHAKNRTYYYHRQYRRVPDITECKEGDVLCIYEAEMQWRRDFKVDQEIMNIIQERLKACQQREGENYQQNCAKELEQFTKVTKAYQDRYLDLGAYYSARKCLAKQKQRMLEERKAARQEAAA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MPDSWDKDVYP ----CCCCCCCCCCC	31.16	23737553
7	Succinylation	-MPDSWDKDVYPEPP -CCCCCCCCCCCCCC	42.72	23954790
7	Acetylation	-MPDSWDKDVYPEPP -CCCCCCCCCCCCCC	42.72	24062335
10	Phosphorylation	DSWDKDVYPEPPSRT CCCCCCCCCCCCCCC	16.41	23984901
15	Phosphorylation	DVYPEPPSRTPAPSP CCCCCCCCCCCCCCC	60.55	23984901
17	Phosphorylation	YPEPPSRTPAPSPQT CCCCCCCCCCCCCCC	28.30	23737553
21	Phosphorylation	PSRTPAPSPQTSLPN CCCCCCCCCCCCCCC	31.57	27742792
24	Phosphorylation	TPAPSPQTSLPNPIT CCCCCCCCCCCCCHH	35.30	26643407
25	Phosphorylation	PAPSPQTSLPNPITY CCCCCCCCCCCCHHH	36.26	26643407
25	O-linked_Glycosylation	PAPSPQTSLPNPITY CCCCCCCCCCCCHHH	36.26	51493393
31	Phosphorylation	TSLPNPITYLTKAYD CCCCCCHHHHHHHHH	17.46	23984901
32	Phosphorylation	SLPNPITYLTKAYDL CCCCCHHHHHHHHHH	17.06	23984901
34	Phosphorylation	PNPITYLTKAYDLVV CCCHHHHHHHHHHHC	11.83	22210690
62	Phosphorylation	QHAKNRTYYYHRQYR HHHHCCCEECCCCCC	9.97	29899451
63	Phosphorylation	HAKNRTYYYHRQYRR HHHCCCEECCCCCCC	7.68	-
125	S-nitrosocysteine	GENYQQNCAKELEQF CCHHHHHHHHHHHHH	5.07	-
125	S-nitrosylation	GENYQQNCAKELEQF CCHHHHHHHHHHHHH	5.07	21278135
125	S-palmitoylation	GENYQQNCAKELEQF CCHHHHHHHHHHHHH	5.07	28526873
127	Succinylation	NYQQNCAKELEQFTK HHHHHHHHHHHHHHH	66.10	26388266
134	Acetylation	KELEQFTKVTKAYQD HHHHHHHHHHHHHHH	49.55	23864654
134	Succinylation	KELEQFTKVTKAYQD HHHHHHHHHHHHHHH	49.55	23954790
151	Phosphorylation	LDLGAYYSARKCLAK HHHHHHHHHHHHHHH	14.66	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NDUBA_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NDUBA_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NDUBA_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of NDUBA_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.