NDUB6_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NDUB6_MOUSE
• UniProt AC: Q3UIU2
• Protein Name: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6
• Gene Name: Ndufb6
• Organism: Mus musculus (Mouse).
• Sequence Length: 128
• Subcellular Localization: Mitochondrion inner membrane ; Single-pass membrane protein ; Matrix side .
• Protein Description: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone..
• Protein Sequence: MSGYTPDEKLRLQQLRELRRRWLKDQELSPREPVLPPRRMWPLERFWDNFLRDGAVWKNMVFKAYRSSLFAVSHVLIPMWFVHYYVKYHMATKPYTIVSSKPRIFPGDTILETGEVIPPMRDFPDQHH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MSGYTPDEK ------CCCCCCCHH	40.27	-
9	Acetylation	SGYTPDEKLRLQQLR CCCCCCHHHHHHHHH	46.41	23954790
24	Acetylation	ELRRRWLKDQELSPR HHHHHHHHCCCCCCC	50.86	23576753
24	Succinylation	ELRRRWLKDQELSPR HHHHHHHHCCCCCCC	50.86	26388266
63	Acetylation	VWKNMVFKAYRSSLF HHHHHHHHHHHHHHH	32.85	23954790
63	Succinylation	VWKNMVFKAYRSSLF HHHHHHHHHHHHHHH	32.85	23954790
93	Acetylation	VKYHMATKPYTIVSS HHHHCCCCCEEEECC	26.87	23806337
93	Succinylation	VKYHMATKPYTIVSS HHHHCCCCCEEEECC	26.87	23806337
99	Phosphorylation	TKPYTIVSSKPRIFP CCCEEEECCCCCCCC	28.88	27841257

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NDUB6_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NDUB6_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NDUB6_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of NDUB6_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.