NDUB5_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NDUB5_MOUSE
• UniProt AC: Q9CQH3
• Protein Name: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial
• Gene Name: Ndufb5
• Organism: Mus musculus (Mouse).
• Sequence Length: 189
• Subcellular Localization: Mitochondrion inner membrane ; Single-pass membrane protein ; Matrix side .
• Protein Description: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone..
• Protein Sequence: MAAMSLLQRASVSALTALSCRRAGPRLGVGSFLTRSFPKTVAPVRHSGDHGKRLFVVKPSLYYDARFLRLMKFYLMLTGIPVIIGITLVNIFIGEAELAEIPEGYIPEHWEYYKHPISRWIARNFYDGPEKNYEKTLAILQIESEKAELRLKEQEVRRLMRARGDGPWYQFPTPEKEFIDHSPKATPDN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
31	Phosphorylation	GPRLGVGSFLTRSFP CCCCCCCCCCCCCCC	18.06	28285833
36	Phosphorylation	VGSFLTRSFPKTVAP CCCCCCCCCCCCEEC	40.44	-
40	Phosphorylation	LTRSFPKTVAPVRHS CCCCCCCCEECCEEC	23.34	-
58	Acetylation	GKRLFVVKPSLYYDA CCEEEEECHHHHHCH	24.48	23864654
58	Succinylation	GKRLFVVKPSLYYDA CCEEEEECHHHHHCH	24.48	23954790
131	Acetylation	NFYDGPEKNYEKTLA HCCCCCCCCHHHHHH	68.88	24062335
136	Phosphorylation	PEKNYEKTLAILQIE CCCCHHHHHHHEEEH	14.96	28494245
144	Phosphorylation	LAILQIESEKAELRL HHHEEEHHHHHHHHH	46.13	28494245
152	Acetylation	EKAELRLKEQEVRRL HHHHHHHHHHHHHHH	51.41	24062335
152	Succinylation	EKAELRLKEQEVRRL HHHHHHHHHHHHHHH	51.41	26388266
176	Acetylation	YQFPTPEKEFIDHSP CCCCCCCHHHCCCCC	60.16	23954790
182	Phosphorylation	EKEFIDHSPKATPDN CHHHCCCCCCCCCCC	25.09	27742792

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NDUB5_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NDUB5_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NDUB5_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of NDUB5_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.