NDUA6_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NDUA6_MOUSE
• UniProt AC: Q9CQZ5
• Protein Name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 {ECO:0000305}
• Gene Name: Ndufa6 {ECO:0000312|MGI:MGI:1914380}
• Organism: Mus musculus (Mouse).
• Sequence Length: 131
• Subcellular Localization: Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side .
• Protein Description: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone..
• Protein Sequence: MAAAATGLRQAAAAAASTSVKPIFSRDLNEAKRRVRELYRAWYREVPNTVHLMQLDITVKQGRDKVREMFMKNAHVTDPRVVDLLVIKGKMELQETIKVWKQRTHVMRFFHETETPRPKDFLSKFYMGHDP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
32	Acetylation	SRDLNEAKRRVRELY CCCHHHHHHHHHHHH	34.26	6568417
90	Acetylation	DLLVIKGKMELQETI HEEEEECCCHHHHHH	24.97	23864654
90	Succinylation	DLLVIKGKMELQETI HEEEEECCCHHHHHH	24.97	23806337

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NDUA6_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NDUA6_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NDUA6_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of NDUA6_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.