NDF4_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NDF4_HUMAN
• UniProt AC: Q9HD90
• Protein Name: Neurogenic differentiation factor 4
• Gene Name: NEUROD4
• Organism: Homo sapiens (Human).
• Sequence Length: 331
• Subcellular Localization: Nucleus .
• Protein Description: Probably acts as a transcriptional activator. Mediates neuronal differentiation. Required for the regulation of amacrine cell fate specification in the retina (By similarity)..
• Protein Sequence: MSKTFVKSKEMGELVNTPSWMDKGLGSQNEVKEEESRPGTYGMLSSLTEEHDSIEEEEEEEEDGEKPKRRGPKKKKMTKARLERFRARRVKANARERTRMHGLNDALDNLRRVMPCYSKTQKLSKIETLRLARNYIWALSEVLETGQTPEGKGFVEMLCKGLSQPTSNLVAGCLQLGPQSVLLEKHEDKSPICDSAISVHNFNYQSPGLPSPPYGHMETHLLHLKPQVFKSLGESSFGSHLPDCSTPPYEGPLTPPLSISGNFSLKQDGSPDLEKSYSFMPHYPSSSLSSGHVHSTPFQAGTPRYDVPIDMSYDSYPHHGIGTQLNTVFTE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	O-linked_Glycosylation	------MSKTFVKSK ------CCCCCCCHH	40.16	30379171
4	Phosphorylation	----MSKTFVKSKEM ----CCCCCCCHHHH	26.76	29759185
8	O-linked_Glycosylation	MSKTFVKSKEMGELV CCCCCCCHHHHHHHC	28.66	30379171
9	Ubiquitination	SKTFVKSKEMGELVN CCCCCCHHHHHHHCC	46.10	-
198	Phosphorylation	PICDSAISVHNFNYQ CCCCCEEEEECCCCC	19.62	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NDF4_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NDF4_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NDF4_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of NDF4_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.