NBPF1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NBPF1_HUMAN
• UniProt AC: Q3BBV0
• Protein Name: Neuroblastoma breakpoint family member 1
• Gene Name: NBPF1
• Organism: Homo sapiens (Human).
• Sequence Length: 1214
• Subcellular Localization: Cytoplasm .
• Protein Sequence: MVVSAGPWSSEKAETNILEINEKLRPQLAENKQQFRNLKEKCFVTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDKPDKSQGQDLQEQLAEGCRLAQQLFQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHSPCDSNQPHKNINITFEEDKVNSTLVVDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKEKCFVTQLACFLANQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDKPDKSQGQDLQEQLAEGCRLAQQLFQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSALVVDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKEKCFVTQLACFLANQQNKYKNEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASCSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMPKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKSYSGTFHSLEEQQVCMAVDIGGHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYILEQQRVGWALDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEAVEPEVLQDSLDRCYSTPSSCLEQPDSCLPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSTKKRRRRGRKEGEEDQNPPCPRLSGMLMEVEEPEVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALDVDNRFLTLMGTSLHLVFQMGVIFPQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
10	Phosphorylation	VSAGPWSSEKAETNI CCCCCCCCCHHHHCH	38.97	-
23	Ubiquitination	NILEINEKLRPQLAE CHHHHHHHHHHHHHH	45.36	29967540
32	Ubiquitination	RPQLAENKQQFRNLK HHHHHHCHHHHHHHH	36.66	29967540
60	Phosphorylation	NRQKKYKYEECKDLI HHHHHCCHHHHHHHH	17.55	21955146
81	Ubiquitination	ERQFKEEKLAEQLKQ HHHHCHHHHHHHHHH	54.83	29967540
139	Phosphorylation	TPDKPDKSQGQDLQE CCCCCCHHCCCCHHH	47.09	-
275	Phosphorylation	TNVSMVVSAGPLSSE CCEEEEEECCCCCCH	18.98	22199227
280	Phosphorylation	VVSAGPLSSEKAEMN EEECCCCCCHHHHCC	39.32	23401153
352	Ubiquitination	ERQFKEEKLAEQLKQ HHHHHHHHHHHHHHH	54.83	29967540
410	Phosphorylation	TPDKPDKSQGQDLQE CCCCCCHHCCCCHHH	47.09	-
546	Phosphorylation	TNVSMVVSAGPLSSE CCEEEEEECCCCCCH	18.98	22199227
551	Phosphorylation	VVSAGPLSSEKAEMN EEECCCCCCHHHHCC	39.32	23401153
602	Phosphorylation	NQQNKYKNEECKDLI HHHCCCCCHHHHHHH	17.55	21955146
681	Phosphorylation	TPDEPDKSQGQDLQE CCCCCCHHCCCCHHH	47.09	-
727	Phosphorylation	VAEKVQKSSAPREMP HHHHHHHCCCCCCCC	18.03	-
728	Phosphorylation	AEKVQKSSAPREMPK HHHHHHCCCCCCCCC	49.69	-
780	Phosphorylation	FEEDKVDSTLIGSSS ECCCCCCCEEECCCC	28.27	-
898	Ubiquitination	SRELLDEKGPEVLQD HHHHHHCCCHHHHHH	78.43	21906983
906	Phosphorylation	GPEVLQDSLDRCYST CHHHHHHHHHHHHCC	21.14	25627689
961	Phosphorylation	VEEDQDPSCPRLSRE HHCCCCCCCHHHHHH	45.07	-
973	Ubiquitination	SRELLDEKEPEVLQD HHHHHCCCCHHHHHH	77.55	21906983
981	Phosphorylation	EPEVLQDSLDRCYST CHHHHHHHHHHHHCC	21.14	23186163
992	Phosphorylation	CYSTPSGYLELPDLG HHCCCCCCCCCCCCC	11.01	-
1056	Phosphorylation	EPEVLQDSLDRCYST CHHHHHHHHHHHCCC	21.14	-
1100	Ubiquitination	LDVGEIEKKGKGKKR CCHHHHHCCCCCCCC	72.92	29967540
1101	Acetylation	DVGEIEKKGKGKKRR CHHHHHCCCCCCCCC	53.73	30705417
1103	Acetylation	GEIEKKGKGKKRRGR HHHHCCCCCCCCCCC	76.16	30705421
1105	Acetylation	IEKKGKGKKRRGRRS HHCCCCCCCCCCCCH	46.74	30705429
1106	Acetylation	EKKGKGKKRRGRRST HCCCCCCCCCCCCHH	56.87	30705425
1114	Acetylation	RRGRRSTKKRRRRGR CCCCCHHHHHHHHHH	45.59	30586325
1151	Phosphorylation	EPEVLQDSLDRCYST CHHHHHHHHHHHCCC	21.14	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NBPF1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NBPF1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NBPF1_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of NBPF1_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.