NAT14_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NAT14_HUMAN
• UniProt AC: Q8WUY8
• Protein Name: N-acetyltransferase 14
• Gene Name: NAT14
• Organism: Homo sapiens (Human).
• Sequence Length: 206
• Subcellular Localization: Membrane ; Single-pass membrane protein .
• Protein Description: Probable acetyltransferase that binds the 5'-GGACTACAG-3' sequence of coproporphyrinogen oxidase promoter. Able to activate transcription of a reporter construct in vitro..
• Protein Sequence: MAPSHLSVREMREDEKPLVLEMLKAGVKDTENRVALHALTRPPALLLLAAASSGLRFVLASFALALLLPVFLAVAAVKLGLRARWGSLPPPGGLGGPWVAVRGSGDVCGVLALAPGTNAGDGARVTRLSVSRWHRRRGVGRRLLAFAEARARAWAGGMGEPRARLVVPVAVAAWGVGGMLEGCGYQAEGGWGCLGYTLVREFSKDL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
87	Phosphorylation	GLRARWGSLPPPGGL CHHHHHCCCCCCCCC	30.64	24719451
104	Phosphorylation	PWVAVRGSGDVCGVL CCEEEECCCCCCEEE	22.66	22210691
126	Phosphorylation	AGDGARVTRLSVSRW CCCCCEEEEEECHHH	21.97	22210691
129	Phosphorylation	GARVTRLSVSRWHRR CCEEEEEECHHHHHH	18.11	24719451
131	Phosphorylation	RVTRLSVSRWHRRRG EEEEEECHHHHHHCC	26.69	22210691

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NAT14_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NAT14_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NAT14_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of NAT14_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.