NANP_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NANP_HUMAN
• UniProt AC: Q8TBE9
• Protein Name: N-acylneuraminate-9-phosphatase
• Gene Name: NANP
• Organism: Homo sapiens (Human).
• Sequence Length: 248
• Protein Sequence: MGLSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYNTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPALLQSIDCKVSMST

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
38	Ubiquitination	VIKLLQSKYHYKEEA HHHHHHHHCCCHHHH	24.08	29967540
41	Phosphorylation	LLQSKYHYKEEAEII HHHHHCCCHHHHHHH	19.60	-
42	Acetylation	LQSKYHYKEEAEIIC HHHHCCCHHHHHHHE	35.45	25953088
51	Ubiquitination	EAEIICDKVQVKLSK HHHHHEEEEEEEECH	30.10	29967540
57	Phosphorylation	DKVQVKLSKECFHPY EEEEEEECHHHCCCC	22.23	17192257
58	Ubiquitination	KVQVKLSKECFHPYN EEEEEECHHHCCCCC	69.78	29967540
83	Phosphorylation	WEEAIQETKGGAANR HHHHHHHCCCCHHHH	20.72	-
84	Ubiquitination	EEAIQETKGGAANRK HHHHHHCCCCHHHHH	55.37	29967540
101	Ubiquitination	EECYFLWKSTRLQHM HHHHHHHHHHHHHCC	44.06	29967540
211	Ubiquitination	KATVWINKNGIVPLK EEEEEECCCCEEECC	47.63	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NANP_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NANP_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NANP_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ESTD_HUMAN	ESD	physical	26344197
LDHB_HUMAN	LDHB	physical	26344197
MIF_HUMAN	MIF	physical	26344197

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.