dbPTM

NADE_RAT - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NADE_RAT
UniProt AC	Q812E8
Protein Name	Glutamine-dependent NAD(+) synthetase
Gene Name	Nadsyn1
Organism	Rattus norvegicus (Rat).
Sequence Length	725
Subcellular Localization
Protein Description
Protein Sequence	MGRKVTVATCALNQWALDFEGNFQRILKSIQIAKGKGARYRLGPELEICGYGCWDHYHESDTLLHSLQVLAALLDAPATQDIICDVGMPIMHRNVRYNCLVIFLNRKILLIRPKMALANEGNYRELRWFTPWARSRQTEEYVLPRMLQDLTKQETVPFGDVVLATQDTCIGSEICEELWTPCSPHVNMGLDGVEIITNASGSHHVLRKAHTRVDLVTMATSKNGGIYLLANQKGCDGHLLYYDGCAMIAMNGSIFAQGTQFSLDDVEVLTATLDLEDVRSYRAKISSRNLEATRVNPYPRVTVDFALSVSEDLLEPVSEPVEWTYHRPEEEISLGPACWLWDFLRRNNQAGFFLPLSGGVDSAASACVVYSMCCLVCEAVKSGNQQVLTDVQNLVDESSYTPQDPRELCGRLLTTCYMASENSSQETHNRATELAQQIGSYHISLNIDPAVKAILGIFSLVTGKFPRFSAHGGSSRENLALQNVQARIRMVLAYLFAQLSLWSRGARGSLLVLGSANVDESLLGYLTKYDCSSADINPIGGISKTDLRAFVQLCAERFQLPVLQAILSAPATAELEPLADGQVSQMDEEDMGMTYTELSIFGRLRKVAKAGPYSMFCKLLNMWKDSCTPRQVAEKVKRFFSKYSINRHKMTTLTPAYHAENYSPDDNRFDLRPFLYNTRWPWQFLCIDNQVVQLERKTSQTLEEQIQEHFKEPSPIWKQLLPKDP

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
28	Ubiquitination	GNFQRILKSIQIAKG CHHHHHHHHHHHHCC	43.04	-
698	Phosphorylation	VVQLERKTSQTLEEQ EEEEHHHHCHHHHHH	32.08	23984901
699	Phosphorylation	VQLERKTSQTLEEQI EEEHHHHCHHHHHHH	24.97	23984901
701	Phosphorylation	LERKTSQTLEEQIQE EHHHHCHHHHHHHHH	35.58	23984901
714	Phosphorylation	QEHFKEPSPIWKQLL HHHHCCCCHHHHHHC	30.06	25575281

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of NADE_RAT !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NADE_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NADE_RAT !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of NADE_RAT !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NADE_RAT

Related Literatures of Post-Translational Modification