| UniProt ID | NAA20_HUMAN | |
|---|---|---|
| UniProt AC | P61599 | |
| Protein Name | N-alpha-acetyltransferase 20 | |
| Gene Name | NAA20 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 178 | |
| Subcellular Localization | Cytoplasm . Nucleus . | |
| Protein Description | Catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp, Met-Glu, Met-Asn and Met-Gln. Proteins with cell cycle functions are overrepresented in the pool of NatB substrates. Required for maintaining the structure and function of actomyosin fibers and for proper cellular migration.. | |
| Protein Sequence | MTTLRAFTCDDLFRFNNINLDPLTETYGIPFYLQYLAHWPEYFIVAEAPGGELMGYIMGKAEGSVAREEWHGHVTALSVAPEFRRLGLAAKLMELLEEISERKGGFFVDLFVRVSNQVAVNMYKQLGYSVYRTVIEYYSASNGEPDEDAYDMRKALSRDTEKKSIIPLPHPVRPEDIE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 103 | Ubiquitination | LEEISERKGGFFVDL HHHHHHHCCCEEEEE | 60.37 | - | |
| 124 | Ubiquitination | QVAVNMYKQLGYSVY HHHHHHHHHHCCHHH | 28.42 | 21890473 | |
| 137 | Phosphorylation | VYRTVIEYYSASNGE HHHHHHHHHHHHCCC | 7.50 | - | |
| 138 | Phosphorylation | YRTVIEYYSASNGEP HHHHHHHHHHHCCCC | 5.74 | - | |
| 157 | Phosphorylation | YDMRKALSRDTEKKS HHHHHHHCCCCCCCC | 32.73 | - | |
| 160 | Phosphorylation | RKALSRDTEKKSIIP HHHHCCCCCCCCCCC | 48.90 | - | |
| 162 | Ubiquitination | ALSRDTEKKSIIPLP HHCCCCCCCCCCCCC | 54.64 | - | |
| 163 | Ubiquitination | LSRDTEKKSIIPLPH HCCCCCCCCCCCCCC | 40.43 | 21890473 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of NAA20_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of NAA20_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of NAA20_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| IKKB_HUMAN | IKBKB | physical | 19716809 | |
| NHEJ1_HUMAN | NHEJ1 | physical | 22939629 | |
| SMAD5_HUMAN | SMAD5 | physical | 22939629 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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