| UniProt ID | N4BP3_MOUSE | |
|---|---|---|
| UniProt AC | Q8C7U1 | |
| Protein Name | NEDD4-binding protein 3 | |
| Gene Name | N4bp3 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 537 | |
| Subcellular Localization | Cytoplasmic vesicle . Cell projection, axon . Cell projection, dendrite . In developing neurons, accumulates in early growth cones and at branching points of axons and dendrites. | |
| Protein Description | Plays a role in axon and dendrite arborization during cranial nerve development. May also be important for neural crest migration and early development of other anterior structures including eye, brain and cranial cartilage.. | |
| Protein Sequence | MATTSGPAGIAMGSVGSLLERQDFSPEELRAALAGSRGSRQPDGLLRKGLGQREFFSYLHLPKKDGKTTKRAPRNEPDYATLYYREHPRAGDFSKTSLPERGRFDKCRIRPSVFKPPVGSGKGFLSMQSLAAHKGQKLWRSNGSLHTLACHPPLSPGPRASQARAQLLHALSLDEGGPEPSLSDSSSGGSFGRSPGTGPSPFSSSLGHINHLGGSLDRAPRSPKESGPLAVLSCLPEPPPPYEFSCPTTEEVAVLPEAREELKRDLGDQDVSNSFTQVLEERQRLWLSELKRLYVERLHEVAQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRTSGSSMEADPNARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELARLREAVHSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEAREGAEQLRAELLQERLRGQEQALRFEQERQTWQEEKERVLRYQREIQGSYMDMYRRNQALEHELRLLREPPTSWSPRLESSKI | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 68 | Phosphorylation | LPKKDGKTTKRAPRN CCCCCCCCCCCCCCC | 42.98 | - | |
| 79 | Phosphorylation | APRNEPDYATLYYRE CCCCCCCCHHEEECC | 16.52 | 22817900 | |
| 96 | Phosphorylation | RAGDFSKTSLPERGR CCCCCCCCCCCCCCC | 34.01 | 30482847 | |
| 97 | Phosphorylation | AGDFSKTSLPERGRF CCCCCCCCCCCCCCC | 45.74 | 30482847 | |
| 126 | Phosphorylation | GSGKGFLSMQSLAAH CCCCCCCHHHHHHHH | 16.71 | 29899451 | |
| 141 | Phosphorylation | KGQKLWRSNGSLHTL CCCCHHHCCCCEEEE | 33.68 | 22817900 | |
| 155 | Phosphorylation | LACHPPLSPGPRASQ EEECCCCCCCCCHHH | 33.32 | 28973931 | |
| 172 | Phosphorylation | AQLLHALSLDEGGPE HHHHHHHCCCCCCCC | 34.26 | 26239621 | |
| 181 | Phosphorylation | DEGGPEPSLSDSSSG CCCCCCCCCCCCCCC | 38.55 | 26239621 | |
| 205 | Phosphorylation | GPSPFSSSLGHINHL CCCCCCCCCCCHHCC | 36.85 | 26370283 | |
| 215 | Phosphorylation | HINHLGGSLDRAPRS CHHCCCCCCCCCCCC | 25.87 | 19367708 | |
| 263 | Ubiquitination | PEAREELKRDLGDQD HHHHHHHHHHHCCCC | 47.33 | 22790023 | |
| 291 | Ubiquitination | RLWLSELKRLYVERL HHHHHHHHHHHHHHH | 35.98 | 22790023 | |
| 529 | Phosphorylation | REPPTSWSPRLESSK HCCCCCCCCCHHCCC | 10.42 | 19854140 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of N4BP3_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of N4BP3_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of N4BP3_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of N4BP3_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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