| UniProt ID | MYPOP_HUMAN | |
|---|---|---|
| UniProt AC | Q86VE0 | |
| Protein Name | Myb-related transcription factor, partner of profilin | |
| Gene Name | MYPOP | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 399 | |
| Subcellular Localization | Nucleus. | |
| Protein Description | Transcriptional repressor; DNA-binding protein that specifically recognizes the core sequence 5'-YAAC[GT]G-3'. Dimerization with PFN1 reduces its DNA-binding capacity (By similarity).. | |
| Protein Sequence | MASAAAGEAEETTRLRKPRFSFEENQILIREVRAHYPQLYGAQSRRVSVAERRRVWDGIAAKINGITSWKRTGQEVQKRWNDFKRRTKEKLARVPHSTQGAGPAAEDAFSAEEETIFAILGPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLPPHDSPPHKRRKGFPTRKRRGRWKSP | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 3 | Phosphorylation | -----MASAAAGEAE -----CCCCCCCCCH | 19.69 | 24043423 | |
| 12 | Phosphorylation | AAGEAEETTRLRKPR CCCCCHHHHCCCCCC | 14.55 | 24043423 | |
| 13 | Phosphorylation | AGEAEETTRLRKPRF CCCCHHHHCCCCCCC | 30.87 | 24043423 | |
| 40 | Phosphorylation | RAHYPQLYGAQSRRV HHHCHHHHCCCCCCC | 12.74 | - | |
| 44 | Phosphorylation | PQLYGAQSRRVSVAE HHHHCCCCCCCCHHH | 22.86 | - | |
| 72 | Phosphorylation | GITSWKRTGQEVQKR CCCCCHHHHHHHHHH | 39.22 | 24702127 | |
| 169 | Phosphorylation | EDRRADTSAHSKAGS HHHHCCCHHHHCCCC | 25.24 | - | |
| 172 | Phosphorylation | RADTSAHSKAGSSSP HCCCHHHHCCCCCCC | 24.74 | - | |
| 176 | Phosphorylation | SAHSKAGSSSPEPWA HHHHCCCCCCCCCCC | 32.28 | 28464451 | |
| 177 | Phosphorylation | AHSKAGSSSPEPWAR HHHCCCCCCCCCCCC | 49.33 | 28450419 | |
| 178 | Phosphorylation | HSKAGSSSPEPWARP HHCCCCCCCCCCCCC | 34.67 | 25159151 | |
| 186 | Phosphorylation | PEPWARPSCTPQEGG CCCCCCCCCCCCCCC | 25.68 | 28985074 | |
| 188 | Phosphorylation | PWARPSCTPQEGGCP CCCCCCCCCCCCCCC | 32.14 | 26074081 | |
| 202 | Phosphorylation | PRPKERESPPPSALQ CCCCCCCCCCCCCCC | 49.26 | 23401153 | |
| 206 | Phosphorylation | ERESPPPSALQPVQL CCCCCCCCCCCCCCC | 47.59 | 23401153 | |
| 279 | Phosphorylation | AIRELAGTLRQGLAK HHHHHHHHHHHHHHH | 17.11 | 22210691 | |
| 378 | Phosphorylation | APLPPHDSPPHKRRK CCCCCCCCCCCCCCC | 36.98 | 30576142 | |
| 389 | Phosphorylation | KRRKGFPTRKRRGRW CCCCCCCCCCCCCCC | 46.70 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MYPOP_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MYPOP_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MYPOP_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of MYPOP_HUMAN !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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