MYO5A_RAT - dbPTM
MYO5A_RAT - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MYO5A_RAT
UniProt AC Q9QYF3
Protein Name Unconventional myosin-Va
Gene Name Myo5a
Organism Rattus norvegicus (Rat).
Sequence Length 1828
Subcellular Localization
Protein Description Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation..
Protein Sequence MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYRLDPKTSELPHLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADSFHYTKQGGSPMIEGVDDAKEMAHTRQACTLLGISESYQMGIFRILAGILHLGNVGFASRDSDSCTIPPKHEPLIIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVGHVNQALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRMSNKAFIIKHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRVPVKPTKGRPGQTAKEHKKTVGLQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLGDRKQTCQNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKRYLCMQRAAITVQRYVRGYQARCYAKFLRRTKAATTIQKYWRMYVVRRKYKIRRAATIVLQSYLRGYLARNRYRKILREHKAVIIQKRVRGWLARTHYKRTMKAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLMEKLTNLEGVYNSETEKLRNDVERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKSIEERADKYKQETEQLVSNLKEENTLLKQEKETLNHLMVEQAKEMTETMERKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMLNVPKPGHKRTDSTHSSNESEYTFSSEFAETEDIAPRTEEPTEKKVPLDMSLFLKLQKRVTELGQEKQLMQDELDRKEEQVLRSKAKGGERPQIRGAELGYESLKRQELESENKKLKNELNELRKALSEKSAPEVNAPGAPAYRVLMEQLTAVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKGKDFQGMLEYKREDEQKLVKNLILELKPRGVAVNLISGLPAYILFMCVRHADYLDDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVRVLENILQPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSILRQLNSFHSVMCQHGMDPELIKQVVKQMFYIVGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGAKETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSFIRTIQVRLRDRKDSPQLLMDAKHIFPVTFPFNPSSLALETIQIPASLGLGFIARV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Acetylation------MAASELYTK
------CCHHHHHHH		30.88-
205PhosphorylationASNPIMESIGNAKTT
HCCHHHHHHCCCCCC		20.5829779826
210UbiquitinationMESIGNAKTTRNDNS
HHHHCCCCCCCCCCC		55.20-
600PhosphorylationQDDEKAISPTSATSS
CCCCCCCCCCCCCCC		27.3030411139
602PhosphorylationDEKAISPTSATSSGR
CCCCCCCCCCCCCCC		24.9723984901
603PhosphorylationEKAISPTSATSSGRT
CCCCCCCCCCCCCCC		32.6923984901
605PhosphorylationAISPTSATSSGRTPL
CCCCCCCCCCCCCCC		24.1625403869
865UbiquitinationRKILREHKAVIIQKR
HHHHHHCCCHHHHHH		39.33-
979UbiquitinationQLSEEEAKVATGRVL
HCCHHHHHHHHHHHH		35.36-
1032PhosphorylationSNLKEENTLLKQEKE
HHHHHHCHHHHHHHH		36.4316641100
1115PhosphorylationPGHKRTDSTHSSNES
CCCCCCCCCCCCCCC		27.6630240740
1116PhosphorylationGHKRTDSTHSSNESE
CCCCCCCCCCCCCCC		28.6930240740
1124PhosphorylationHSSNESEYTFSSEFA
CCCCCCCEEECCCHH		23.5125532521
1277UbiquitinationRSQLVSQKEAIQPKD
HHHHHCCHHCCCCCC		41.42-
1283UbiquitinationQKEAIQPKDDKNTMT
CHHCCCCCCCCCCCC		63.28-
1394AcetylationDLMEQLEKQDKTVRK
HHHHHHHHHHHHHHH		72.8322902405
1425PhosphorylationVGQMENISPGQIIDE
CCCCCCCCCCCCCCC		34.2627097102
1469AcetylationKNLILELKPRGVAVN
HHHHHHCCCCCEEHH		24.2422902405
1514AcetylationTSTINSIKKVLKKRG
HHHHHHHHHHHHHCC		36.338263741
1623PhosphorylationPTGLRKRTSSIADEG
CCCCCHHCCCCCCCC		29.8427097102
1624PhosphorylationTGLRKRTSSIADEGT
CCCCHHCCCCCCCCC		24.6327097102
1625PhosphorylationGLRKRTSSIADEGTY
CCCHHCCCCCCCCCC		22.6023712012
1631PhosphorylationSSIADEGTYTLDSIL
CCCCCCCCCCHHHHH		15.9828551015
1632PhosphorylationSIADEGTYTLDSILR
CCCCCCCCCHHHHHH		19.0328551015
1730AcetylationAAQLLQVKKKTDDDA
HHHHHHHHCCCCCCH		35.278264571
1733PhosphorylationLLQVKKKTDDDAEAI
HHHHHCCCCCCHHHH		54.24-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MYO5A_RAT !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MYO5A_RAT !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MYO5A_RAT !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of MYO5A_RAT !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MYO5A_RAT

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Related Literatures of Post-Translational Modification

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