MYO1B_MOUSE - dbPTM
MYO1B_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MYO1B_MOUSE
UniProt AC P46735
Protein Name Unconventional myosin-Ib
Gene Name Myo1b
Organism Mus musculus (Mouse).
Sequence Length 1107
Subcellular Localization
Protein Description Motor protein that may participate in process critical to neuronal development and function such as cell migration, neurite outgrowth and vesicular transport..
Protein Sequence MAKMEVKSSLLDNMIGVGDMVLLEPLNEETFIDNLKKRFDHNEIYTYIGSVVISVNPYRSLPIYSPEKVEDYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQPRGERNFHVFYQLLSGASEELLYKLKLERDFSRYNYLSLDSAKVNGVDDAANFRTVRNAMQIVGFLDHEAEAVLEVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTSIDQVVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFESRMSKCSRFLNDTTLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKAGHSLIKSLFPEGNPAKVNLKRPPTAGSQFKASVATLMRNLQTKNPNYIRCIKPNDKKAAHIFNESLVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELEIPVEEHSFGRSKIFIRNPRTLFQLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKRSQVVIAAWYRRYAQQKRYQQIKSSALVIQSYIRGWKARKILRELKHQKRCKEAATTIAAYWHGTQARRELKRLKEEARRKHAVAVIWAYWLGLKVRREYRKFFRANAGKKIYEFTLQRIVQKYLLEMKNKMPSLSPIDKNWPSRPYLFLDSTHKELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKALYPSSVGQPFQGAYLEINKNPKYKKLKDAIEEKIIIAEVVNKINRANGKSTSRIFLLTNNNLLLADQKSGQIKSEVPLVDVTKVSMSSQNDGFFAVHLKEGSEAASKGDFLFSSDHLIEMATKLYRTTLSQTKQKLNIEISDEFLVQFRQDKVCVKFIQGNQKNGSVPTCKRKNNRLLEVAVP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
59MethylationVISVNPYRSLPIYSP
EEEECCCCCCCCCCH		32.7318964941
59DimethylationVISVNPYRSLPIYSP
EEEECCCCCCCCCCH		32.73-
60PhosphorylationISVNPYRSLPIYSPE
EEECCCCCCCCCCHH		32.4325338131
68UbiquitinationLPIYSPEKVEDYRNR
CCCCCHHHHHHHCCC		55.07-
123PhosphorylationEASKLVMSYVAAVCG
HHHHHHHHHHHHHHC		14.6929109428
129S-palmitoylationMSYVAAVCGKGAEVN
HHHHHHHHCCCHHHH		3.9028526873
156UbiquitinationLEAFGNAKTVRNDNS
HHHHCCCEEECCCCC		52.10-
157PhosphorylationEAFGNAKTVRNDNSS
HHHCCCEEECCCCCC		23.45-
164PhosphorylationTVRNDNSSRFGKYMD
EECCCCCCCCEEEEE		37.5726824392
192UbiquitinationISNYLLEKSRVVKQP
HHHHHHHHHCCCCCC		43.46-
241UbiquitinationYLSLDSAKVNGVDDA
EEECCCCCCCCCCCH		39.94-
287AcetylationKLGNIEFKPESRVNG
HHCCCCCCCHHHCCC		34.7823954790
301AcetylationGLDESKIKDKNELKE
CCCHHHCCCHHHHHH		67.4023201123
325PhosphorylationVVLERAFSFRTVEAK
HHHHHHHCCEEECCC		16.9129514104
509S-palmitoylationDTTLPHSCFRIQHYA
CCCCCCHHHHHHHCC		2.1228526873
529UbiquitinationQVEGFVDKNNDLLYR
EEEECCCCCCCCHHH		52.96-
548PhosphorylationAMWKAGHSLIKSLFP
HHHHHHHHHHHHHCC		30.7629472430
561MalonylationFPEGNPAKVNLKRPP
CCCCCCCCCCCCCCC		32.6726320211
565UbiquitinationNPAKVNLKRPPTAGS
CCCCCCCCCCCCCCH		58.62-
577PhosphorylationAGSQFKASVATLMRN
CCHHHHHHHHHHHHH		16.9328059163
580PhosphorylationQFKASVATLMRNLQT
HHHHHHHHHHHHHHC		20.9421183079
588UbiquitinationLMRNLQTKNPNYIRC
HHHHHHCCCCCCEEE		58.40-
662PhosphorylationHWKGPARSGVEVLFN
CCCCCCCCCCEEEEE		49.6626239621
747PhosphorylationRYAQQKRYQQIKSSA
HHHHHHHHHHHHHHH		16.2921454597
753PhosphorylationRYQQIKSSALVIQSY
HHHHHHHHHHHHHHH		22.1821454597
906UbiquitinationDQFTDQQKLIYEEKL
HCCCHHHHHHHHHHH		31.08-
916PhosphorylationYEEKLEASELFKDKK
HHHHHHHHHHHCCCC		26.0027180971
938PhosphorylationGQPFQGAYLEINKNP
CCCCCCCEEEECCCC		16.2229514104
943UbiquitinationGAYLEINKNPKYKKL
CCEEEECCCCCHHHH		79.06-
957UbiquitinationLKDAIEEKIIIAEVV
HHHHHHHHHHHHHHH		26.81-
993PhosphorylationLLLADQKSGQIKSEV
EEECCCCCCCCCCCC		30.2325777480
998PhosphorylationQKSGQIKSEVPLVDV
CCCCCCCCCCEEEEE		45.5125777480
1006PhosphorylationEVPLVDVTKVSMSSQ
CCEEEEEEEEEECCC		22.6725777480
1009PhosphorylationLVDVTKVSMSSQNDG
EEEEEEEEECCCCCC		17.9525777480
1011PhosphorylationDVTKVSMSSQNDGFF
EEEEEEECCCCCCEE		22.6725777480
1012PhosphorylationVTKVSMSSQNDGFFA
EEEEEECCCCCCEEE		25.1025777480
1023UbiquitinationGFFAVHLKEGSEAAS
CEEEEEECCCCHHHH		45.19-
1057UbiquitinationRTTLSQTKQKLNIEI
HHHHHHHHHHHCCEE		37.49-
1080UbiquitinationRQDKVCVKFIQGNQK
CCCCEEEEEECCCCC		31.46-
1087UbiquitinationKFIQGNQKNGSVPTC
EEECCCCCCCCCCCC		68.24-
1093PhosphorylationQKNGSVPTCKRKNNR
CCCCCCCCCCCCCCE		28.6221183079
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MYO1B_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MYO1B_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MYO1B_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of MYO1B_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MYO1B_MOUSE

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Related Literatures of Post-Translational Modification

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