| UniProt ID | MYO12_ARATH | |
|---|---|---|
| UniProt AC | F4IRU3 | |
| Protein Name | Myosin-12 | |
| Gene Name | XI-F | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 1556 | |
| Subcellular Localization | ||
| Protein Description | Myosin heavy chain that is required for the cell cycle-regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables (By similarity).. | |
| Protein Sequence | MGTPVNITLGSHVWVEDPELAWISGEVTEIKGTNAKIVTANGKTVVASISSIYPKDTEAPPAGVDDMTKLAYLHEPGVLHNLDCRFALNEIYTYTGNILIAVNPFQRLPHLYSVHMMEQYKGAAFGELSPHLFAVADTSYRAMINEARSQSILVSGESGAGKTETTKMLMRYLAFMGGRSDTEGRSVEQQVLESNPVLEAFGNAKTVKNNNSSRFGKFVEIQFDKRGKISGAAIRTYLLERSRVCQVSDPERNYHCFYMLCAAPPEEAKKFKVGDPRTFHYLNQTNCYEVSNVDDAREYLETRNAMDIVGIGQEAQDAIFRVVAAILHLGNVNFIKGEEADSSKLRDDKSRYHLQTAAELLMCNEKMMEDSLCKRVIVTPDGNITKPLDPESAASNRDALAKTVYSRLFDWIVDKINSSIGQDPDAKSLIGVLDIYGFESFKINSFEQLCINLTNEKLQQHFNQHVFKMEQEEYTREEINWSYVEFVDNQDVLDLIEKKPGGIIALLDEACMFPKSTHETFAQKMYQTYKGHKRFSKPKLAQTAFTVNHYAGDVTYSAEQFLDKNKDYVVAEHQALLDASKCSFVANLFPPLPEDASKQSKFSSIGTRFKQQLQALMETLNTTEPHYIRCVKPNAVLKPGIFENDNVLNQLRCGGVLEAIRISCAGYPTKRAFDEFLDRFVMLATDVPEGSDEKSACASICNKMGLKGYQIGKTKIFLRAGQMAELDARRTEVLAGATKLIQRQIRTYLTRKEFLGQKRATIYMQKLWRAKLARKLYQNMRREAASICIQKNIRAHRARKNYTKLQASATVIQTGLRTMSARNKHRHRRRTKAAIIIQREWRRHQVHEAYKKHKKATLALQCLWRAKVARKELKNLRMAARETGALKEAKDKLEKRVEELTWRLELEKNQKADLEDAKAQEIAKLQNNLTELQEKLDEAYAAIIRDKEAAKLAIEQAPPIIKEVPVVDNTQLELLNSQNNELEVEVAKLKGKIKEFEVKCFALENDSRASVTEAEDAKSKAVEFQEIIERLHTNLSNLESENQVLRQQALAASTSVEEIGELNSLKDKVAILESENETLRRQTESAEKTMPPARVFASEKNLENEHQTKEIQATKEPRNPINVLAKQGSLTDRQQESHEVLMKCLTDERRFDNEKSVAAWIVYKALLQWRLFEAEKTNIFDRIVHKIRSSIEGQDDTRELAYWLTTSSTLLYLLQSTLKFSNTNNAASRRNRSSHATLFGRLVQGMQPSSVGLETSSGYSGMAGIPNDQQMVEAKYPALLFKQHLAAYVEKTYGMIRDKLKKEINPLLNLCIHAPRPTRAKTLRDVTKSIHLTTIAKQQASYVQWQNIVNKLEHTLTFMAENHVPSMITRKLFHQVFSYINVQLFNSLLLRRECCSVSNGEYLKMGLHELEQWCLKADDEATRSPWDELQHIRQAVMFLVSHQKTQKSLDEIAKEICPVLSIPQVYRIGTMFWDDKYGTQGLSPEVINQMRKLMTEDSANMTYPSFLLDVDSSIPFSVEDVSQSFHGGNISLSDVDPSPLLRQRSDFHFLFQTLPE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 236 | Phosphorylation | ISGAAIRTYLLERSR CCHHHHHHHHHHHCC | 19880383 | ||
| 242 | Phosphorylation | RTYLLERSRVCQVSD HHHHHHHCCCCCCCC | 24894044 | ||
| 709 | Phosphorylation | NKMGLKGYQIGKTKI HHCCCCCEEECCEEE | 22074104 | ||
| 1223 | Phosphorylation | STLKFSNTNNAASRR HHHHCCCCCCHHHHC | 22074104 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MYO12_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MYO12_ARATH !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MYO12_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of MYO12_ARATH !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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