MYL6B_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MYL6B_MOUSE
• UniProt AC: Q8CI43
• Protein Name: Myosin light chain 6B
• Gene Name: Myl6b {ECO:0000312|EMBL:AAH37527.1, ECO:0000312|MGI:MGI:1917789}
• Organism: Mus musculus (Mouse).
• Sequence Length: 207
• Protein Description: Regulatory light chain of myosin. Does not bind calcium..
• Protein Sequence: MPPKKDAPVKKPAGPSISKPAAKSTPGTPLAKAKAEPAAPQAPAKSQEPPVDLSKVVIEFNKDQLEEFREAFELFDRVGDGKILYSQCGDLMRALGQNPTNAEVLKVLGNPKNEELKSRRVDFETFLPMLQAVAKNRDQGTYEDYLEGLRVFDKEGNGKVMGAELRHVLTTLGEKMTEEEVETVLAGHEDSNGCINYEAFLKHILSL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
16	Phosphorylation	VKKPAGPSISKPAAK CCCCCCCCCCCCCCC	38.28	22871156
24	Phosphorylation	ISKPAAKSTPGTPLA CCCCCCCCCCCCCHH	34.80	24899341
25	Phosphorylation	SKPAAKSTPGTPLAK CCCCCCCCCCCCHHH	25.65	22871156
28	Phosphorylation	AAKSTPGTPLAKAKA CCCCCCCCCHHHHCC	19.14	24719451
86	Phosphorylation	GDGKILYSQCGDLMR CCCCEEEHHHHHHHH	18.62	-
100	Phosphorylation	RALGQNPTNAEVLKV HHHCCCCCCHHHHHH	55.39	-
106	Acetylation	PTNAEVLKVLGNPKN CCCHHHHHHHCCCCC	40.36	22638941
106	Ubiquitination	PTNAEVLKVLGNPKN CCCHHHHHHHCCCCC	40.36	27667366

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MYL6B_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MYL6B_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MYL6B_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of MYL6B_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.