MYL4_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MYL4_HUMAN
• UniProt AC: P12829
• Protein Name: Myosin light chain 4
• Gene Name: MYL4
• Organism: Homo sapiens (Human).
• Sequence Length: 197
• Protein Description: Regulatory light chain of myosin. Does not bind calcium..
• Protein Sequence: MAPKKPEPKKEAAKPAPAPAPAPAPAPAPAPEAPKEPAFDPKSVKIDFTADQIEEFKEAFSLFDRTPTGEMKITYGQCGDVLRALGQNPTNAEVLRVLGKPKPEEMNVKMLDFETFLPILQHISRNKEQGTYEDFVEGLRVFDKESNGTVMGAELRHVLATLGEKMTEAEVEQLLAGQEDANGCINYEAFVKHIMSG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Methylation	------MAPKKPEPK ------CCCCCCCCC	25.31	-
66	Phosphorylation	AFSLFDRTPTGEMKI HHHCCCCCCCCCCEE	27.35	11557734
74	Phosphorylation	PTGEMKITYGQCGDV CCCCCEEEEECHHHH	18.97	-
75	Phosphorylation	TGEMKITYGQCGDVL CCCCEEEEECHHHHH	14.52	26437602
90	Phosphorylation	RALGQNPTNAEVLRV HHHCCCCCCHHHHHH	55.39	-
132	Phosphorylation	RNKEQGTYEDFVEGL CCCCCCCHHHHHHHE	21.96	-
146	Phosphorylation	LRVFDKESNGTVMGA EEEEEECCCCEECHH	46.42	-
149	Phosphorylation	FDKESNGTVMGAELR EEECCCCEECHHHHH	16.15	-
161	Phosphorylation	ELRHVLATLGEKMTE HHHHHHHHHCHHCCH	31.00	26437602
165	Acetylation	VLATLGEKMTEAEVE HHHHHCHHCCHHHHH	49.69	30590597
196	Phosphorylation	AFVKHIMSG------ HHHHHHHCC------	40.52	11557734

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MYL4_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MYL4_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MYL4_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PYRD2_HUMAN	PYROXD2	physical	21988832

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.