MYH6_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MYH6_MOUSE
• UniProt AC: Q02566
• Protein Name: Myosin-6
• Gene Name: Myh6
• Organism: Mus musculus (Mouse).
• Sequence Length: 1938
• Subcellular Localization: Cytoplasm, myofibril. Thick filaments of the myofibrils.
• Protein Description: Muscle contraction..
• Protein Sequence: MTDAQMADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEYVKAKVVSREGGKVTAETENGKTVTIKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRSKKENPNANKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLDMLLVTNNPYDYAFVSQGEVSVASIDDSEELLATDSAFDVLSFTAEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKSVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKASDMTFKAKLYDNHLGKSNNFQKPRNVKGKQEAHFSLVHYAGTVDYNIMGWLEKNKDPLNETVVGLYQKSSLKLMATLFSTYASADTGDSGKGKGGKKKGSSFQTVSALHRENLNKLMTNLKTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDSRKGAEKLLGSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMANMKEEFGRVKDALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDISQQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSSRHDCDLLREQYEEEMEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKIRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRMVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSQANRIASEAQKHLKNSQAHLKDTQLQLDDAVHANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLMRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGAKKMHDEE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
21	Ubiquitination	QYLRKSEKERLEAQT HHHHHHHHHHHHHHC	56.05	-
28	Phosphorylation	KERLEAQTRPFDIRT HHHHHHHCCCCCCCC	47.56	22817900
37	S-nitrosocysteine	PFDIRTECFVPDDKE CCCCCCCEECCCCHH	4.05	-
37	S-nitrosylation	PFDIRTECFVPDDKE CCCCCCCEECCCCHH	4.05	21278135
43	Acetylation	ECFVPDDKEEYVKAK CEECCCCHHHHEEEE	60.88	24062335
43	Ubiquitination	ECFVPDDKEEYVKAK CEECCCCHHHHEEEE	60.88	-
48	Ubiquitination	DDKEEYVKAKVVSRE CCHHHHEEEEEEECC	41.40	-
53	Phosphorylation	YVKAKVVSREGGKVT HEEEEEEECCCCEEE	27.83	22324799
58	Ubiquitination	VVSREGGKVTAETEN EEECCCCEEEEEEEC	47.47	-
67	Ubiquitination	TAETENGKTVTIKED EEEEECCEEEEECHH	51.94	-
70	Phosphorylation	TENGKTVTIKEDQVM EECCEEEEECHHHHH	31.40	27742792
72	Ubiquitination	NGKTVTIKEDQVMQQ CCEEEEECHHHHHCC	45.96	-
83	Ubiquitination	VMQQNPPKFDKIEDM HHCCCCCCCCHHHHH	68.41	-
129	"N6,N6,N6-trimethyllysine"	CVTVNPYKWLPVYNA EEEECCCCEEEECCH	43.44	-
129	Methylation	CVTVNPYKWLPVYNA EEEECCCCEEEECCH	43.44	-
173	Phosphorylation	LTDRENQSILITGES CCCCCCCEEEEECCC	30.83	27742792
177	Phosphorylation	ENQSILITGESGAGK CCCEEEEECCCCCCC	31.30	27742792
180	Phosphorylation	SILITGESGAGKTVN EEEEECCCCCCCCCC	34.98	27742792
184	Ubiquitination	TGESGAGKTVNTKRV ECCCCCCCCCCHHHH	49.09	-
197	Phosphorylation	RVIQYFASIAAIGDR HHHHHHHHHHHHCCC	11.67	-
206	Ubiquitination	AAIGDRSKKENPNAN HHHCCCCCCCCCCCC	66.07	17451654
207	Ubiquitination	AIGDRSKKENPNANK HHCCCCCCCCCCCCC	65.06	17451654
214	Ubiquitination	KENPNANKGTLEDQI CCCCCCCCCCHHHHH	51.35	17451654
216	Phosphorylation	NPNANKGTLEDQIIQ CCCCCCCCHHHHHHH	28.69	22817900
235	Ubiquitination	LEAFGNAKTVRNDNS HHHHCCCEEECCCCC	52.10	-
236	Phosphorylation	EAFGNAKTVRNDNSS HHHCCCEEECCCCCC	23.45	-
243	Phosphorylation	TVRNDNSSRFGKFIR EECCCCCCCCCEEEE	37.57	26824392
247	Acetylation	DNSSRFGKFIRIHFG CCCCCCCEEEEEEEC	34.60	133193
256	Phosphorylation	IRIHFGATGKLASAD EEEEECCCCCCCCCC	34.92	23737553
258	Acetylation	IHFGATGKLASADIE EEECCCCCCCCCCHH	36.20	15612455
261	Phosphorylation	GATGKLASADIETYL CCCCCCCCCCHHHHH	36.59	28542873
271	Ubiquitination	IETYLLEKSRVIFQL HHHHHHHHCEEEEEE	43.46	-
279	Ubiquitination	SRVIFQLKAERNYHI CEEEEEEEHHCCHHH	37.10	-
351	Phosphorylation	AEEKAGVYKLTGAIM HHHHCCCCHHHHHHH	10.20	22817900
352	Methylation	EEKAGVYKLTGAIMH HHHCCCCHHHHHHHH	36.85	-
352	Ubiquitination	EEKAGVYKLTGAIMH HHHCCCCHHHHHHHH	36.85	-
354	Phosphorylation	KAGVYKLTGAIMHYG HCCCCHHHHHHHHHC	22.03	22817900
364	Ubiquitination	IMHYGNMKFKQKQRE HHHHCCCCCHHHHHH	54.10	-
368	Ubiquitination	GNMKFKQKQREEQAE CCCCCHHHHHHHHCC	52.49	-
379	Phosphorylation	EQAEPDGTEDADKSA HHCCCCCCCCHHHHH	37.76	23737553
384	Ubiquitination	DGTEDADKSAYLMGL CCCCCHHHHHHHHCC	38.41	-
385	Phosphorylation	GTEDADKSAYLMGLN CCCCHHHHHHHHCCC	23.77	23737553
387	Phosphorylation	EDADKSAYLMGLNSA CCHHHHHHHHCCCHH	12.33	23737553
398	Ubiquitination	LNSADLLKGLCHPRV CCHHHHHHCCCCCCE	58.07	-
406	Ubiquitination	GLCHPRVKVGNEYVT CCCCCCEEECCEEEC	45.78	-
411	Phosphorylation	RVKVGNEYVTKGQSV CEEECCEEECCCCCH	19.88	21183079
413	Phosphorylation	KVGNEYVTKGQSVQQ EECCEEECCCCCHHH	28.67	23737553
417	Phosphorylation	EYVTKGQSVQQVYYS EEECCCCCHHHHHHH	30.48	-
451	Ubiquitination	INATLETKQPRQYFI HHHHCCCCCCCCEEE	49.26	-
503	Ubiquitination	VLEQEEYKKEGIEWE EECHHHHHHCCCCEE	47.86	-
550	Methylation	KASDMTFKAKLYDNH CCCCCCEEEEHHHCC	35.13	-
560	Methylation	LYDNHLGKSNNFQKP HHHCCCCCCCCCCCC	57.27	-
560	Ubiquitination	LYDNHLGKSNNFQKP HHHCCCCCCCCCCCC	57.27	-
566	Acetylation	GKSNNFQKPRNVKGK CCCCCCCCCCCCCCC	41.63	7923535
566	Ubiquitination	GKSNNFQKPRNVKGK CCCCCCCCCCCCCCC	41.63	-
599	Ubiquitination	MGWLEKNKDPLNETV HHHHHHCCCCCCCHH	72.32	-
605	Phosphorylation	NKDPLNETVVGLYQK CCCCCCCHHHHHHHH	21.30	28464351
610	Phosphorylation	NETVVGLYQKSSLKL CCHHHHHHHHHHHHH	14.15	28542873
612	Ubiquitination	TVVGLYQKSSLKLMA HHHHHHHHHHHHHHH	28.58	-
623	Phosphorylation	KLMATLFSTYASADT HHHHHHHHHHHCCCC	24.50	23737553
624	Phosphorylation	LMATLFSTYASADTG HHHHHHHHHHCCCCC	18.77	23737553
627	Phosphorylation	TLFSTYASADTGDSG HHHHHHHCCCCCCCC	19.10	23737553
630	Phosphorylation	STYASADTGDSGKGK HHHHCCCCCCCCCCC	42.47	24719451
633	Phosphorylation	ASADTGDSGKGKGGK HCCCCCCCCCCCCCC	43.69	23737553
635	Ubiquitination	ADTGDSGKGKGGKKK CCCCCCCCCCCCCCC	62.49	-
642	Methylation	KGKGGKKKGSSFQTV CCCCCCCCCCCHHHH	68.46	-
642	Ubiquitination	KGKGGKKKGSSFQTV CCCCCCCCCCCHHHH	68.46	-
644	Phosphorylation	KGGKKKGSSFQTVSA CCCCCCCCCHHHHHH	36.54	23737553
645	Phosphorylation	GGKKKGSSFQTVSAL CCCCCCCCHHHHHHH	30.00	23737553
648	Phosphorylation	KKGSSFQTVSALHRE CCCCCHHHHHHHCHH	17.89	23737553
650	Phosphorylation	GSSFQTVSALHRENL CCCHHHHHHHCHHHH	28.62	27742792
659	Ubiquitination	LHRENLNKLMTNLKT HCHHHHHHHHHHHCC	42.68	-
665	Ubiquitination	NKLMTNLKTTHPHFV HHHHHHHCCCCCCEE	54.14	-
666	Phosphorylation	KLMTNLKTTHPHFVR HHHHHHCCCCCCEEE	33.24	24899341
667	Phosphorylation	LMTNLKTTHPHFVRC HHHHHCCCCCCEEEE	31.64	24899341
681	Ubiquitination	CIIPNERKAPGVMDN EECCCCCCCCCCCCC	53.40	-
697	S-nitrosocysteine	LVMHQLRCNGVLEGI CHHHHHHHCCHHHHH	7.65	-
697	S-nitrosylation	LVMHQLRCNGVLEGI CHHHHHHHCCHHHHH	7.65	21278135
740	Phosphorylation	PEGQFIDSRKGAEKL CCCCCCCCCCCHHHH	30.95	23737553
746	Ubiquitination	DSRKGAEKLLGSLDI CCCCCHHHHHCCCCC	48.77	-
750	Phosphorylation	GAEKLLGSLDIDHNQ CHHHHHCCCCCCCCC	23.88	23737553
759	Acetylation	DIDHNQYKFGHTKVF CCCCCCCCCCCHHHH	34.80	7923547
759	Ubiquitination	DIDHNQYKFGHTKVF CCCCCCCCCCCHHHH	34.80	-
764	Ubiquitination	QYKFGHTKVFFKAGL CCCCCCHHHHHHHHH	31.22	-
784	Phosphorylation	EMRDERLSRIITRIQ HHHHHHHHHHHHHHH	27.88	23737553
837	Ubiquitination	PWMKLYFKIKPLLKS HHHHHHHHHHHHHHC	35.94	-
843	Ubiquitination	FKIKPLLKSAETEKE HHHHHHHHCHHHHHH	56.13	-
849	Ubiquitination	LKSAETEKEMANMKE HHCHHHHHHHHHHHH	61.28	-
855	Ubiquitination	EKEMANMKEEFGRVK HHHHHHHHHHHHHHH	54.63	-
867	Ubiquitination	RVKDALEKSEARRKE HHHHHHHHHHHHHHH	55.22	-
878	Ubiquitination	RRKELEEKMVSLLQE HHHHHHHHHHHHHHH	34.91	-
881	Phosphorylation	ELEEKMVSLLQEKND HHHHHHHHHHHHHCC	21.62	23737553
907	S-nitrosocysteine	LNDAEERCDQLIKNK CHHHHHHHHHHHHHH	4.41	-
907	S-nitrosylation	LNDAEERCDQLIKNK CHHHHHHHHHHHHHH	4.41	21278135
912	Ubiquitination	ERCDQLIKNKIQLEA HHHHHHHHHHHHHHH	61.86	-
914	Ubiquitination	CDQLIKNKIQLEAKV HHHHHHHHHHHHHHH	27.16	-
920	Ubiquitination	NKIQLEAKVKEMTER HHHHHHHHHHHHHHH	44.45	-
922	Ubiquitination	IQLEAKVKEMTERLE HHHHHHHHHHHHHCC	40.85	-
941	Ubiquitination	MNAELTAKKRKLEDE HHHHHHHHHHHHHHH	48.12	-
944	Ubiquitination	ELTAKKRKLEDECSE HHHHHHHHHHHHHHH	66.17	-
949	S-nitrosocysteine	KRKLEDECSELKKDI HHHHHHHHHHHHHCH	6.23	-
949	S-nitrosylation	KRKLEDECSELKKDI HHHHHHHHHHHHHCH	6.23	21278135
950	Phosphorylation	RKLEDECSELKKDID HHHHHHHHHHHHCHH	43.87	27742792
953	Acetylation	EDECSELKKDIDDLE HHHHHHHHHCHHHHH	44.33	160917
953	Ubiquitination	EDECSELKKDIDDLE HHHHHHHHHCHHHHH	44.33	-
954	Ubiquitination	DECSELKKDIDDLEL HHHHHHHHCHHHHHH	72.96	-
962	Phosphorylation	DIDDLELTLAKVEKE CHHHHHHHHHHHHHH	18.46	22210690
965	Ubiquitination	DLELTLAKVEKEKHA HHHHHHHHHHHHHHC	54.78	-
968	Ubiquitination	LTLAKVEKEKHATEN HHHHHHHHHHHCCHH	75.05	-
978	Ubiquitination	HATENKVKNLTEEMA HCCHHHHHHHHHHHC	48.09	-
981	Phosphorylation	ENKVKNLTEEMAGLD HHHHHHHHHHHCCHH	39.01	-
999	Ubiquitination	AKLTKEKKALQEAHQ HHHHHHHHHHHHHHH	56.26	-
1018	Ubiquitination	DLQAEEDKVNTLTKS HHHHHHHHHHHHHHH	40.44	-
1021	Phosphorylation	AEEDKVNTLTKSKVK HHHHHHHHHHHHHHH	38.50	21183079
1023	Phosphorylation	EDKVNTLTKSKVKLE HHHHHHHHHHHHHHH	31.10	21183079
1024	Ubiquitination	DKVNTLTKSKVKLEQ HHHHHHHHHHHHHHH	51.93	-
1026	Ubiquitination	VNTLTKSKVKLEQQV HHHHHHHHHHHHHHH	44.97	-
1028	Ubiquitination	TLTKSKVKLEQQVDD HHHHHHHHHHHHHHH	50.47	-
1039	Phosphorylation	QVDDLEGSLEQEKKV HHHHCCCCHHHHHHH	21.25	27742792
1044	Ubiquitination	EGSLEQEKKVRMDLE CCCHHHHHHHHHHHH	57.15	-
1056	Ubiquitination	DLERAKRKLEGDLKL HHHHHHHHHHHCHHC	50.62	-
1062	Ubiquitination	RKLEGDLKLTQESIM HHHHHCHHCCHHHHH	54.98	-
1064	Phosphorylation	LEGDLKLTQESIMDL HHHCHHCCHHHHHHH	28.80	23737553
1067	Phosphorylation	DLKLTQESIMDLEND CHHCCHHHHHHHHCC	17.25	23737553
1075	Ubiquitination	IMDLENDKLQLEEKL HHHHHCCHHHHHHHH	50.11	-
1081	Ubiquitination	DKLQLEEKLKKKEFD CHHHHHHHHHHCCCC	57.12	-
1090	Phosphorylation	KKKEFDISQQNSKIE HHCCCCHHHCCCCCC	27.79	23737553
1094	Phosphorylation	FDISQQNSKIEDEQA CCHHHCCCCCCHHHH	30.58	22817900
1095	Ubiquitination	DISQQNSKIEDEQAL CHHHCCCCCCHHHHH	58.63	-
1108	Ubiquitination	ALALQLQKKLKENQA HHHHHHHHHHHHHHH	69.53	-
1109	Ubiquitination	LALQLQKKLKENQAR HHHHHHHHHHHHHHH	52.40	-
1129	Phosphorylation	EELEAERTARAKVEK HHHHHHHHHHHHHHH	16.41	22817900
1139	Phosphorylation	AKVEKLRSDLSRELE HHHHHHHHHHHHHHH	54.03	27742792
1142	Phosphorylation	EKLRSDLSRELEEIS HHHHHHHHHHHHHHH	28.79	23737553
1149	Phosphorylation	SRELEEISERLEEAG HHHHHHHHHHHHHCC	21.68	28542873
1159	Phosphorylation	LEEAGGATSVQIEMN HHHCCCCCEEEEECC	32.48	23737553
1160	Phosphorylation	EEAGGATSVQIEMNK HHCCCCCEEEEECCH	16.10	23737553
1167	Ubiquitination	SVQIEMNKKREAEFQ EEEEECCHHHHHHHH	52.47	-
1175	Ubiquitination	KREAEFQKMRRDLEE HHHHHHHHHHHHHHH	39.43	-
1184	Phosphorylation	RRDLEEATLQHEATA HHHHHHHHHHHHHHH	30.17	28464351
1190	Phosphorylation	ATLQHEATAAALRKK HHHHHHHHHHHHHHH	17.53	22210690
1197	Ubiquitination	TAAALRKKHADSVAE HHHHHHHHHHHHHHH	37.28	-
1201	Phosphorylation	LRKKHADSVAELGEQ HHHHHHHHHHHHHHH	24.82	25521595
1221	Ubiquitination	RVKQKLEKEKSEFKL HHHHHHHHHHHCCCE	79.48	-
1224	Phosphorylation	QKLEKEKSEFKLELD HHHHHHHHCCCEEHH	49.73	23737553
1227	Ubiquitination	EKEKSEFKLELDDVT HHHHHCCCEEHHHHC	36.68	-
1234	Phosphorylation	KLELDDVTSNMEQII CEEHHHHCCCHHHHH	22.75	23737553
1235	Phosphorylation	LELDDVTSNMEQIIK EEHHHHCCCHHHHHH	33.74	23737553
1242	Ubiquitination	SNMEQIIKAKANLEK CCHHHHHHHHHHHHH	45.52	-
1249	Ubiquitination	KAKANLEKVSRTLED HHHHHHHHHHHHHHH	48.99	-
1251	Phosphorylation	KANLEKVSRTLEDQA HHHHHHHHHHHHHHH	30.53	27742792
1253	Phosphorylation	NLEKVSRTLEDQANE HHHHHHHHHHHHHHH	27.30	27742792
1261	Phosphorylation	LEDQANEYRVKLEEA HHHHHHHHHHHHHHH	22.10	23737553
1264	Ubiquitination	QANEYRVKLEEAQRS HHHHHHHHHHHHHHH	40.98	-
1271	Phosphorylation	KLEEAQRSLNDFTTQ HHHHHHHHHHHHHHH	21.31	23737553
1277	Phosphorylation	RSLNDFTTQRAKLQT HHHHHHHHHHHHHHC	18.95	-
1281	Ubiquitination	DFTTQRAKLQTENGE HHHHHHHHHHCCCHH	43.23	17451654
1284	Phosphorylation	TQRAKLQTENGELAR HHHHHHHCCCHHHHH	41.68	23737553
1296	Ubiquitination	LARQLEEKEALISQL HHHHHHHHHHHHHHH	38.62	-
1301	Phosphorylation	EEKEALISQLTRGKL HHHHHHHHHHHHCCC	21.71	23737553
1304	Phosphorylation	EALISQLTRGKLSYT HHHHHHHHHCCCHHH	29.73	27742792
1307	Ubiquitination	ISQLTRGKLSYTQQM HHHHHHCCCHHHHHH	30.85	-
1309	Phosphorylation	QLTRGKLSYTQQMED HHHHCCCHHHHHHHH	29.62	23737553
1310	Phosphorylation	LTRGKLSYTQQMEDL HHHCCCHHHHHHHHH	21.00	23737553
1311	Phosphorylation	TRGKLSYTQQMEDLK HHCCCHHHHHHHHHH	14.67	27742792
1318	Acetylation	TQQMEDLKRQLEEEG HHHHHHHHHHHHHHH	50.88	160909
1318	Ubiquitination	TQQMEDLKRQLEEEG HHHHHHHHHHHHHHH	50.88	-
1326	Ubiquitination	RQLEEEGKAKNALAH HHHHHHHHHHHHHHH	60.51	-
1328	Ubiquitination	LEEEGKAKNALAHAL HHHHHHHHHHHHHHH	46.36	-
1337	Phosphorylation	ALAHALQSSRHDCDL HHHHHHHHCHHHHHH	30.14	24899341
1338	Phosphorylation	LAHALQSSRHDCDLL HHHHHHHCHHHHHHH	22.22	27742792
1342	S-nitrosocysteine	LQSSRHDCDLLREQY HHHCHHHHHHHHHHH	3.03	-
1342	S-nitrosylation	LQSSRHDCDLLREQY HHHCHHHHHHHHHHH	3.03	21278135
1349	Phosphorylation	CDLLREQYEEEMEAK HHHHHHHHHHHHHHH	22.13	27742792
1356	Ubiquitination	YEEEMEAKAELQRVL HHHHHHHHHHHHHHH	29.14	-
1364	Phosphorylation	AELQRVLSKANSEVA HHHHHHHHHHHHHHH	27.19	27742792
1365	Ubiquitination	ELQRVLSKANSEVAQ HHHHHHHHHHHHHHH	47.64	-
1368	Phosphorylation	RVLSKANSEVAQWRT HHHHHHHHHHHHHHH	38.00	24899341
1375	Phosphorylation	SEVAQWRTKYETDAI HHHHHHHHHHHHHHH	34.71	27742792
1376	Acetylation	EVAQWRTKYETDAIQ HHHHHHHHHHHHHHH	32.30	55169653
1376	Ubiquitination	EVAQWRTKYETDAIQ HHHHHHHHHHHHHHH	32.30	-
1377	Phosphorylation	VAQWRTKYETDAIQR HHHHHHHHHHHHHHH	24.37	23737553
1379	Phosphorylation	QWRTKYETDAIQRTE HHHHHHHHHHHHHHH	27.86	28542873
1385	Phosphorylation	ETDAIQRTEELEEAK HHHHHHHHHHHHHHH	19.89	28464351
1392	Acetylation	TEELEEAKKKLAQRL HHHHHHHHHHHHHHH	54.44	19863205
1392	Ubiquitination	TEELEEAKKKLAQRL HHHHHHHHHHHHHHH	54.44	-
1393	Ubiquitination	EELEEAKKKLAQRLQ HHHHHHHHHHHHHHH	61.13	-
1412	Ubiquitination	AVEAVNAKCSSLEKT HHHHHHHHCHHHHHH	29.46	-
1413	S-nitrosocysteine	VEAVNAKCSSLEKTK HHHHHHHCHHHHHHH	2.87	-
1413	S-nitrosylation	VEAVNAKCSSLEKTK HHHHHHHCHHHHHHH	2.87	21278135
1418	Ubiquitination	AKCSSLEKTKHRLQN HHCHHHHHHHHHHHH	69.07	-
1446	Ubiquitination	AAAAALDKKQRNFDK HHHHHHHHHHHCHHH	52.21	-
1447	Ubiquitination	AAAALDKKQRNFDKI HHHHHHHHHHCHHHH	54.91	-
1453	Ubiquitination	KKQRNFDKILAEWKQ HHHHCHHHHHHHHHH	35.17	-
1459	Ubiquitination	DKILAEWKQKYEESQ HHHHHHHHHHHHHHH	28.54	-
1461	Ubiquitination	ILAEWKQKYEESQSE HHHHHHHHHHHHHHH	51.40	-
1462	Phosphorylation	LAEWKQKYEESQSEL HHHHHHHHHHHHHHH	23.57	27742792
1465	Phosphorylation	WKQKYEESQSELESS HHHHHHHHHHHHHHH	27.37	23737553
1467	Phosphorylation	QKYEESQSELESSQK HHHHHHHHHHHHHHH	54.12	23737553
1471	Phosphorylation	ESQSELESSQKEARS HHHHHHHHHHHHHHH	51.17	27742792
1472	Phosphorylation	SQSELESSQKEARSL HHHHHHHHHHHHHHH	35.58	27742792
1474	Ubiquitination	SELESSQKEARSLST HHHHHHHHHHHHHHH	56.12	-
1478	Phosphorylation	SSQKEARSLSTELFK HHHHHHHHHHHHHHH	33.45	27742792
1480	Phosphorylation	QKEARSLSTELFKLK HHHHHHHHHHHHHHH	22.53	24899341
1481	Phosphorylation	KEARSLSTELFKLKN HHHHHHHHHHHHHHH	41.84	27742792
1485	Ubiquitination	SLSTELFKLKNAYEE HHHHHHHHHHHHHHH	71.78	-
1487	Ubiquitination	STELFKLKNAYEESL HHHHHHHHHHHHHHH	39.87	-
1490	Phosphorylation	LFKLKNAYEESLEHL HHHHHHHHHHHHHHH	29.62	27742792
1493	Phosphorylation	LKNAYEESLEHLETF HHHHHHHHHHHHHHH	27.41	23737553
1499	Phosphorylation	ESLEHLETFKRENKN HHHHHHHHHHHHCCC	40.59	27742792
1501	Acetylation	LEHLETFKRENKNLQ HHHHHHHHHHCCCHH	67.24	160913
1501	Ubiquitination	LEHLETFKRENKNLQ HHHHHHHHHHCCCHH	67.24	-
1505	Ubiquitination	ETFKRENKNLQEEIS HHHHHHCCCHHHHHH	55.04	-
1512	Phosphorylation	KNLQEEISDLTEQLG CCHHHHHHHHHHHHC	29.82	23737553
1515	Phosphorylation	QEEISDLTEQLGEGG HHHHHHHHHHHCCCC	27.03	-
1523	Ubiquitination	EQLGEGGKNVHELEK HHHCCCCCCHHHHHH	67.65	-
1530	Ubiquitination	KNVHELEKIRKQLEV CCHHHHHHHHHHHHH	61.51	-
1533	Ubiquitination	HELEKIRKQLEVEKL HHHHHHHHHHHHHHH	63.81	-
1539	Ubiquitination	RKQLEVEKLELQSAL HHHHHHHHHHHHHHH	53.06	17451654
1544	Phosphorylation	VEKLELQSALEEAEA HHHHHHHHHHHHHHH	47.66	22817900
1552	Phosphorylation	ALEEAEASLEHEEGK HHHHHHHHHHHHCHH	26.29	23737553
1559	Ubiquitination	SLEHEEGKILRAQLE HHHHHCHHHHHHHHH	41.68	-
1571	Ubiquitination	QLEFNQIKAEIERKL HHHHHHHHHHHHHHH	30.15	17451654
1577	Ubiquitination	IKAEIERKLAEKDEE HHHHHHHHHHHHHHH	38.98	-
1581	Ubiquitination	IERKLAEKDEEMEQA HHHHHHHHHHHHHHH	65.91	-
1589	Acetylation	DEEMEQAKRNHLRMV HHHHHHHHHHHHHHH	54.12	160745
1589	Ubiquitination	DEEMEQAKRNHLRMV HHHHHHHHHHHHHHH	54.12	-
1598	Phosphorylation	NHLRMVDSLQTSLDA HHHHHHHHHHHHCCH	15.80	23737553
1601	Phosphorylation	RMVDSLQTSLDAETR HHHHHHHHHCCHHHC	36.23	27742792
1602	Phosphorylation	MVDSLQTSLDAETRS HHHHHHHHCCHHHCC	15.99	27742792
1607	Phosphorylation	QTSLDAETRSRNEAL HHHCCHHHCCHHHHH	35.35	27742792
1609	Phosphorylation	SLDAETRSRNEALRV HCCHHHCCHHHHHHH	47.05	23737553
1618	Ubiquitination	NEALRVKKKMEGDLN HHHHHHHHHHCCCCC	55.27	-
1619	Ubiquitination	EALRVKKKMEGDLNE HHHHHHHHHCCCCCH	36.14	-
1632	Phosphorylation	NEMEIQLSQANRIAS CHHHHHHHHHHHHHH	15.75	27742792
1639	Phosphorylation	SQANRIASEAQKHLK HHHHHHHHHHHHHHH	30.97	23737553
1643	Ubiquitination	RIASEAQKHLKNSQA HHHHHHHHHHHHHHH	58.93	-
1646	Ubiquitination	SEAQKHLKNSQAHLK HHHHHHHHHHHHHHH	55.03	-
1653	Ubiquitination	KNSQAHLKDTQLQLD HHHHHHHHHCHHHHH	49.19	-
1670	Ubiquitination	VHANDDLKENIAIVE HCCCCCHHHHHHHHH	56.56	-
1702	Ubiquitination	EQTERSRKLAEQELI HHHHHHHHHHHHHHH	53.98	-
1711	Phosphorylation	AEQELIETSERVQLL HHHHHHHHHHHHHHH	28.97	27742792
1712	Phosphorylation	EQELIETSERVQLLH HHHHHHHHHHHHHHH	15.60	27742792
1720	Phosphorylation	ERVQLLHSQNTSLIN HHHHHHHHCCHHHHH	25.70	23737553
1723	Phosphorylation	QLLHSQNTSLINQKK HHHHHCCHHHHHHHH	19.78	23737553
1724	Phosphorylation	LLHSQNTSLINQKKK HHHHCCHHHHHHHHH	34.50	23737553
1729	Ubiquitination	NTSLINQKKKMESDL CHHHHHHHHHHHHHH	50.28	-
1734	Phosphorylation	NQKKKMESDLTQLQT HHHHHHHHHHHHHHH	34.13	-
1737	Phosphorylation	KKMESDLTQLQTEVE HHHHHHHHHHHHHHH	32.02	21183079
1750	S-nitrosocysteine	VEEAVQECRNAEEKA HHHHHHHHHCHHHHH	1.96	-
1750	S-nitrosylation	VEEAVQECRNAEEKA HHHHHHHHHCHHHHH	1.96	21278135
1759	Ubiquitination	NAEEKAKKAITDAAM CHHHHHHHHHHHHHH	50.29	-
1762	Phosphorylation	EKAKKAITDAAMMAE HHHHHHHHHHHHHHH	25.17	28464351
1777	Phosphorylation	ELKKEQDTSAHLERM HHHHHHCCHHHHHHH	27.75	28464351
1778	Phosphorylation	LKKEQDTSAHLERMK HHHHHCCHHHHHHHH	23.21	28464351
1786	Ubiquitination	AHLERMKKNMEQTIK HHHHHHHHHHHHHHH	52.78	-
1793	Ubiquitination	KNMEQTIKDLQHRLD HHHHHHHHHHHHHHH	56.63	-
1808	Ubiquitination	EAEQIALKGGKKQLQ HHHHHHHHHCHHHHH	57.50	-
1811	Ubiquitination	QIALKGGKKQLQKLE HHHHHHCHHHHHHHH	46.12	-
1812	Ubiquitination	IALKGGKKQLQKLEA HHHHHCHHHHHHHHH	60.56	-
1816	Ubiquitination	GGKKQLQKLEARVRE HCHHHHHHHHHHHHH	57.81	-
1833	Ubiquitination	NELEAEQKRNAESVK HHHHHHHHHCHHHHC	38.84	-
1840	Ubiquitination	KRNAESVKGMRKSER HHCHHHHCCHHHHHH	57.16	-
1843	Methylation	AESVKGMRKSERRIK HHHHCCHHHHHHHHH	48.28	16188097
1850	Ubiquitination	RKSERRIKELTYQTE HHHHHHHHHHHCCCH	44.88	-
1853	Phosphorylation	ERRIKELTYQTEEDK HHHHHHHHCCCHHHH	18.06	27742792
1854	Phosphorylation	RRIKELTYQTEEDKK HHHHHHHCCCHHHHH	26.51	27742792
1856	Phosphorylation	IKELTYQTEEDKKNL HHHHHCCCHHHHHHH	30.81	23737553
1860	Ubiquitination	TYQTEEDKKNLMRLQ HCCCHHHHHHHHHHH	47.01	-
1861	Ubiquitination	YQTEEDKKNLMRLQD CCCHHHHHHHHHHHH	68.58	-
1872	Succinylation	RLQDLVDKLQLKVKA HHHHHHHHHHHHHHH	30.56	26388266
1872	Ubiquitination	RLQDLVDKLQLKVKA HHHHHHHHHHHHHHH	30.56	-
1876	Succinylation	LVDKLQLKVKAYKRQ HHHHHHHHHHHHHHH	28.82	26388266
1876	Ubiquitination	LVDKLQLKVKAYKRQ HHHHHHHHHHHHHHH	28.82	-
1878	Ubiquitination	DKLQLKVKAYKRQAE HHHHHHHHHHHHHHH	44.40	-
1893	Phosphorylation	EAEEQANTNLSKFRK HHHHHHCCCHHHHHH	40.32	27742792
1896	Phosphorylation	EQANTNLSKFRKVQH HHHCCCHHHHHHHHH	31.64	23737553
1897	Ubiquitination	QANTNLSKFRKVQHE HHCCCHHHHHHHHHH	52.97	-
1900	Ubiquitination	TNLSKFRKVQHELDE CCHHHHHHHHHHHHH	49.75	-
1917	Phosphorylation	ERADIAESQVNKLRA HHHHHHHHHHHHHHH	30.33	23737553
1921	Ubiquitination	IAESQVNKLRAKSRD HHHHHHHHHHHHHCC	40.26	-
1926	Phosphorylation	VNKLRAKSRDIGAKK HHHHHHHHCCCCCCC	33.91	23737553
1932	Ubiquitination	KSRDIGAKKMHDEE- HHCCCCCCCCCCCC-	45.47	-
1933	Ubiquitination	SRDIGAKKMHDEE-- HCCCCCCCCCCCC--	40.72	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MYH6_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MYH6_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MYH6_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of MYH6_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Ubiquitylation

"A proteomics approach to identify the ubiquitinated proteins in mouseheart.";
Jeon H.B., Choi E.S., Yoon J.H., Hwang J.H., Chang J.W., Lee E.K.,Choi H.W., Park Z.-Y., Yoo Y.J.;
Biochem. Biophys. Res. Commun. 357:731-736(2007).
Cited for: UBIQUITINATION [LARGE SCALE ANALYSIS] AT LYS-206; LYS-207; LYS-214;LYS-1281; LYS-1539 AND LYS-1571, AND MASS SPECTROMETRY.
PubMed: 17451654