| UniProt ID | MYBPH_MOUSE | |
|---|---|---|
| UniProt AC | P70402 | |
| Protein Name | Myosin-binding protein H | |
| Gene Name | Mybph | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 483 | |
| Subcellular Localization | ||
| Protein Description | Binds to myosin; probably involved in interaction with thick myofilaments in the A-band.. | |
| Protein Sequence | MTGKATSEASVSTPEETAPEPAKVPTTEPSGEVAASESTGQEQAPEPQKPQAQDPAAPAASAMPAATKPEPPSEDVPSAPLRLTLEDVSHSSLTVSWEPPEKLGKLGLQGYVLEFCREGASEWVPVNPRPVMVTQQTVRNLALGDKFFLRVTAVSSAGAGPPAVLDQPVHIQEITEAPKIRVPRHLRQTYIRQVGESVNLQIPFQGKPKPQVSWTHNGHALDNQRVNVRSGDQDSILFIRSAQRADSGRYELTVHLEGLEAKASIDILVIEKPGPPSSIKLLDVWGCNAALEWTPPQDTGNTELLGYTVQKADKRTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSDLATTTKELAHIHKADITAKPREFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMDIQGDPKYRAVSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASATH | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Phosphorylation | ------MTGKATSEA ------CCCCCCCCC | 47.60 | - | |
| 6 | Phosphorylation | --MTGKATSEASVST --CCCCCCCCCCCCC | 30.50 | - | |
| 6 | O-linked_Glycosylation | --MTGKATSEASVST --CCCCCCCCCCCCC | 30.50 | 30016717 | |
| 7 | Phosphorylation | -MTGKATSEASVSTP -CCCCCCCCCCCCCC | 35.70 | 28464351 | |
| 12 | Phosphorylation | ATSEASVSTPEETAP CCCCCCCCCCCCCCC | 35.43 | 28464351 | |
| 13 | Phosphorylation | TSEASVSTPEETAPE CCCCCCCCCCCCCCC | 32.34 | 24899341 | |
| 26 | Phosphorylation | PEPAKVPTTEPSGEV CCCCCCCCCCCCCCC | 46.94 | - | |
| 105 | Ubiquitination | EPPEKLGKLGLQGYV CCHHHHCCCCCCCCH | 50.22 | 22790023 | |
| 146 | Ubiquitination | RNLALGDKFFLRVTA HHHHCCCCEEEEEEE | 35.90 | 22790023 | |
| 156 | Phosphorylation | LRVTAVSSAGAGPPA EEEEEECCCCCCCCC | 24.91 | 28464351 | |
| 189 | Phosphorylation | VPRHLRQTYIRQVGE CCHHHHHHHHHHHCC | 17.93 | 28542873 | |
| 190 | Phosphorylation | PRHLRQTYIRQVGES CHHHHHHHHHHHCCC | 5.93 | 28542873 | |
| 197 | Phosphorylation | YIRQVGESVNLQIPF HHHHHCCCEEEECCC | 15.46 | 21454597 | |
| 277 | Phosphorylation | IEKPGPPSSIKLLDV ECCCCCCCCEEEEEE | 48.07 | 28464351 | |
| 278 | Phosphorylation | EKPGPPSSIKLLDVW CCCCCCCCEEEEEEE | 29.53 | 28464351 | |
| 360 | Phosphorylation | GLSDLATTTKELAHI CHHHHHHHHHHHHHH | 30.20 | 28464351 | |
| 410 | Phosphorylation | YSTQLFCSVRASPKP CCEEEEEEEECCCCC | 13.80 | - | |
| 451 | Phosphorylation | TLEIRKPSPFDSGVY EEEECCCCCCCCCEE | 41.03 | 28542873 | |
| 461 | Ubiquitination | DSGVYTCKAINVLGE CCCEEEEEEEEEEEC | 44.49 | - | |
| 480 | Phosphorylation | CRLEVKASATH---- EEEEEEECCCC---- | 28.16 | 28464351 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MYBPH_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MYBPH_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MYBPH_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of MYBPH_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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