| UniProt ID | MYBPH_HUMAN | |
|---|---|---|
| UniProt AC | Q13203 | |
| Protein Name | Myosin-binding protein H | |
| Gene Name | MYBPH | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 477 | |
| Subcellular Localization | ||
| Protein Description | Binds to myosin; probably involved in interaction with thick myofilaments in the A-band.. | |
| Protein Sequence | MMEKNTSEGPACSPEETASESAKVPTAEPPGEVAVSESTREEQVPKPQAPAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAAH | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 6 | Phosphorylation | --MMEKNTSEGPACS --CCCCCCCCCCCCC | 38.94 | - | |
| 26 | Phosphorylation | SESAKVPTAEPPGEV CCCCCCCCCCCCCCE | 46.79 | - | |
| 56 | Phosphorylation | APAPQAPTASTATKP CCCCCCCCCCCCCCC | 35.93 | - | |
| 183 | Phosphorylation | VPRHLRQTYIRQVGE CCHHHHHHHHHHHCC | 17.93 | 24719451 | |
| 184 | Phosphorylation | PRHLRQTYIRQVGET CHHHHHHHHHHHCCE | 5.93 | 26437602 | |
| 244 | Phosphorylation | QRSDSGRYELTVRVE ECCCCCCEEEEEEHH | 20.86 | 29083192 | |
| 247 | Phosphorylation | DSGRYELTVRVEDLE CCCCEEEEEEHHHHH | 8.37 | 29083192 | |
| 427 | Ubiquitination | MEIQGNPKYRALSEQ EEECCCHHHHHHHHC | 51.90 | 21890473 | |
| 445 | Phosphorylation | TLEIRKPSPFDSGVY EEEECCCCCCCCCEE | 41.03 | 26437602 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MYBPH_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MYBPH_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MYBPH_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of MYBPH_HUMAN !! | ||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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