dbPTM

MXRA8_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	MXRA8_MOUSE
UniProt AC	Q9DBV4
Protein Name	Matrix remodeling-associated protein 8
Gene Name	Mxra8
Organism	Mus musculus (Mouse).
Sequence Length	442
Subcellular Localization	Membrane Single-pass type I membrane protein.
Protein Description	May play a role in the maturation and maintenance of blood-brain barrier..
Protein Sequence	MELLSRVLLWKLLLLQSSAVLSSGPSGTAAASSSLVSESVVSLAAGTQAVLRCQSPRMVWTQDRLHDRQRVVHWDLSGGPGSQRRRLVDMYSAGEQRVYEPRDRDRLLLSPSAFHDGNFSLLIRAVDRGDEGVYTCNLHHHYCHLDESLAVRLEVTEDPLLSRAYWDGEKEVLVVAHGAPALMTCINRAHVWTDRHLEEAQQVVHWDRQLPGVSHDRADRLLDLYASGERRAYGPPFLRDRVSVNTNAFARGDFSLRIDELERADEGIYSCHLHHHYCGLHERRVFHLQVTEPAFEPPARASPGNGSGHSSAPSPDPTLTRGHSIINVIVPEDHTHFFQQLGYVLATLLLFILLLITVVLATRYRHSGGCKTSDKKAGKSKGKDVNMVEFAVATRDQAPYRTEDIQLDYKNNILKERAELAHSPLPAKDVDLDKEFRKEYCK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
118	N-linked_Glycosylation	PSAFHDGNFSLLIRA CHHHCCCCEEEEEEE	29.41	-
227	Phosphorylation	RLLDLYASGERRAYG HHHHHHHCCCCHHCC	27.85	24899341
246	Ubiquitination	RDRVSVNTNAFARGD CCCEEECCCCHHCCC	26.26	27667366
305	N-linked_Glycosylation	PARASPGNGSGHSSA CCCCCCCCCCCCCCC	44.86	-
409	Phosphorylation	TEDIQLDYKNNILKE CCCCCCHHHCCHHHH	24.98	22817900
410	Ubiquitination	EDIQLDYKNNILKER CCCCCHHHCCHHHHH	43.09	22790023
423	Phosphorylation	ERAELAHSPLPAKDV HHHHHCCCCCCHHHC	23.64	26824392
425	Ubiquitination	AELAHSPLPAKDVDL HHHCCCCCCHHHCCC	7.84	27667366
428	Ubiquitination	AHSPLPAKDVDLDKE CCCCCCHHHCCCCHH	57.24	27667366
440	Phosphorylation	DKEFRKEYCK----- CHHHHHHHCC-----	14.47	29514104

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of MXRA8_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of MXRA8_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of MXRA8_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of MXRA8_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of MXRA8_MOUSE

Related Literatures of Post-Translational Modification