MUG70_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MUG70_SCHPO
• UniProt AC: O13965
• Protein Name: Meiotically up-regulated gene 70 protein
• Gene Name: mug70
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 730
• Subcellular Localization: Cytoplasm. Nucleus membrane; Multi-pass membrane protein.
• Protein Description: Has a role in meiosis..
• Protein Sequence: MTVGTLSVVSSTASDTASHVSDTRKRQYQRDEALRKKIISELGKKSGNFESPVRKIRRNGEPGTVDSAALDPALTVHMQSLVTETAQLMAAKRQNCVLVVDDDEQLAGIVTATDIATRCVGAGLNARQTLIADIMSTSPLCITSDTRFDDALLLMIEHKFRHLPVVSDGGPDGSAGDEGDVIGIINMRACLREPLNRIARQQEAAQKLVEALEGAQEEIENKSVSGNTNSSSVSGNHAAEFLEYVESLKKKASGLEIMSLIDSSEEPFLVGTRTTVAEATESMARSGVSAVLVMDNGAVSGVFTAHDVVLRVLAAGLDPYRSSVIRVMTPHPDCALASLRVSTALERMIEGKFSNLPVVDESDAIIGMLSLFHLATAIEQTPEEEEEVFDQAENDAGIEPSNGFEDQQQQLLGNSNEVVENYDVNPPLPLNPLPSNTQQSESTYEYSARQLPKPPVQAWQNENLSSNNKPQEYVGVENDYNFSNNPPTAMSEQSFHPSVSQKPMDTPENGSNSFAASPYLQPYNSASQLAPSYVGSLPQYHGNPSFVEQALQDLVQPTDSASQIFPLNPQSPSQFTIKYRSIAGRVHRLRLDGINSVSDLRTAVEEREKEQLVTLTYIDDEGDVVELVSDSDLREAILLARRRGLPRLEVRGVAAFTNHLESSHPPISTVDSSIGSASVVEKGVANSIVDIHQPTAKADKGNSKKPIYIGIVSSSIVILAVSMWYLRRKR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MTVGTLSVV ------CCCEEEEEE	27.87	24763107
5	Phosphorylation	---MTVGTLSVVSST ---CCCEEEEEEECC	16.12	29996109
7	Phosphorylation	-MTVGTLSVVSSTAS -CCCEEEEEEECCCC	21.95	24763107
10	Phosphorylation	VGTLSVVSSTASDTA CEEEEEEECCCCHHH	21.58	21712547
12	Phosphorylation	TLSVVSSTASDTASH EEEEEECCCCHHHHC	23.75	29996109
14	Phosphorylation	SVVSSTASDTASHVS EEEECCCCHHHHCCC	35.27	21712547
16	Phosphorylation	VSSTASDTASHVSDT EECCCCHHHHCCCHH	27.80	28889911
18	Phosphorylation	STASDTASHVSDTRK CCCCHHHHCCCHHHH	26.89	24763107
21	Phosphorylation	SDTASHVSDTRKRQY CHHHHCCCHHHHHHH	28.04	21712547
51	Phosphorylation	KKSGNFESPVRKIRR HHCCCCCCCHHHHHH	25.26	24763107
223	Phosphorylation	QEEIENKSVSGNTNS HHHHHHCCCCCCCCC	32.85	24763107
225	Phosphorylation	EIENKSVSGNTNSSS HHHHCCCCCCCCCCC	33.16	21712547
228	Phosphorylation	NKSVSGNTNSSSVSG HCCCCCCCCCCCCCC	39.75	21712547
230	Phosphorylation	SVSGNTNSSSVSGNH CCCCCCCCCCCCCHH	23.19	21712547
231	Phosphorylation	VSGNTNSSSVSGNHA CCCCCCCCCCCCHHH	36.51	21712547
232	Phosphorylation	SGNTNSSSVSGNHAA CCCCCCCCCCCHHHH	21.81	21712547
234	Phosphorylation	NTNSSSVSGNHAAEF CCCCCCCCCHHHHHH	35.51	21712547
672	Phosphorylation	PPISTVDSSIGSASV CCCCCCCCCCCCHHH	21.37	29996109
678	Phosphorylation	DSSIGSASVVEKGVA CCCCCCHHHHHCCCC	28.52	29996109
687	Phosphorylation	VEKGVANSIVDIHQP HHCCCCCCEEEECCC	17.79	24763107

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MUG70_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MUG70_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MUG70_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
YOXA_SCHPO	SPBC14F5.10c	physical	26771498

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.