MUC7_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MUC7_HUMAN
• UniProt AC: Q8TAX7
• Protein Name: Mucin-7
• Gene Name: MUC7
• Organism: Homo sapiens (Human).
• Sequence Length: 377
• Subcellular Localization: Secreted .
• Protein Description: May function in a protective capacity by promoting the clearance of bacteria in the oral cavity and aiding in mastication, speech, and swallowing. Binds P.aeruginosa pili..
• Protein Sequence: MKTLPLFVCICALSACFSFSEGRERDHELRHRRHHHQSPKSHFELPHYPGLLAHQKPFIRKSYKCLHKRCRPKLPPSPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAPDTSETSAAPTHQTTTSVTTQTTTTKQPTSAPGQNKISRFLLYMKNLLNRIIDDMVEQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
38	Phosphorylation	HRRHHHQSPKSHFEL HHHHCCCCCCHHCCC	29.91	26657352
41	Phosphorylation	HHHQSPKSHFELPHY HCCCCCCHHCCCCCC	36.47	21299198
48	Phosphorylation	SHFELPHYPGLLAHQ HHCCCCCCCCHHHHC	9.32	26657352
97	N-linked_Glycosylation	PPKHPDKNSSVVNPT CCCCCCCCCCCCCCE	47.07	UniProtKB CARBOHYD
128	N-linked_Glycosylation	TKITTLPNVTFLPQN CEEEECCCCEEECCC	48.88	UniProtKB CARBOHYD
128	N-linked_Glycosylation	TKITTLPNVTFLPQN CEEEECCCCEEECCC	48.88	17623646
135	N-linked_Glycosylation	NVTFLPQNATTISSR CCEEECCCCCCCCCC	37.00	17623646
135	N-linked_Glycosylation	NVTFLPQNATTISSR CCEEECCCCCCCCCC	37.00	UniProtKB CARBOHYD
146	N-linked_Glycosylation	ISSRENVNTSSSVAT CCCCCCCCCCCCEEE	45.91	17623646
146	N-linked_Glycosylation	ISSRENVNTSSSVAT CCCCCCCCCCCCEEE	45.91	UniProtKB CARBOHYD
176	O-linked_Glycosylation	PPTPSATTPAPPSSS CCCCCCCCCCCCCCC	19.71	12135769
176	O-linked_Glycosylation	PPTPSATTPAPPSSS CCCCCCCCCCCCCCC	19.71	-
199	O-linked_Glycosylation	PPTPSATTQAPPSSS CCCCCCCCCCCCCCC	23.58	12135769
199	O-linked_Glycosylation	PPTPSATTQAPPSSS CCCCCCCCCCCCCCC	23.58	-
222	O-linked_Glycosylation	PPTPPATTPAPPSSS CCCCCCCCCCCCCCC	21.40	12135769
222	O-linked_Glycosylation	PPTPPATTPAPPSSS CCCCCCCCCCCCCCC	21.40	-
245	O-linked_Glycosylation	PPTPSATTPAPLSSS CCCCCCCCCCCCCCC	19.71	-
245	O-linked_Glycosylation	PPTPSATTPAPLSSS CCCCCCCCCCCCCCC	19.71	12135769
268	O-linked_Glycosylation	PPTPSATTLDPSSAS CCCCCCCCCCHHHCC	28.96	-
268	O-linked_Glycosylation	PPTPSATTLDPSSAS CCCCCCCCCCHHHCC	28.96	12135769
291	O-linked_Glycosylation	PPTPSATTPAPPSSP CCCCCCCCCCCCCCC	19.71	-
291	O-linked_Glycosylation	PPTPSATTPAPPSSP CCCCCCCCCCCCCCC	19.71	12135769
362	Phosphorylation	KISRFLLYMKNLLNR HHHHHHHHHHHHHHH	14.27	22461510

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MUC7_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MUC7_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MUC7_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of MUC7_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• 600807: Asthma (ASTHMA)
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.