MTL26_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MTL26_HUMAN
• UniProt AC: Q96S19
• Protein Name: Methyltransferase-like 26 {ECO:0000312|HGNC:HGNC:14141}
• Gene Name: METTL26 {ECO:0000312|HGNC:HGNC:14141}
• Organism: Homo sapiens (Human).
• Sequence Length: 204
• Protein Sequence: MLVAAAAERNKDPILHVLRQYLDPAQRGVRVLEVASGSGQHAAHFARAFPLAEWQPSDVDQRCLDSIAATTQAQGLTNVKAPLHLDVTWGWEHWGGILPQSLDLLLCINMAHVSPLRCTEGLFRAAGHLLKPRALLITYGPYAINGKISPQSNVDFDLMLRCRNPEWGLRDTALLEDLGKASGLLLERMVDMPANNKCLIFRKN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MLVAAAAE -------CCHHHHHH		22814378
11	Ubiquitination	AAAAERNKDPILHVL HHHHHHCCCHHHHHH		-
114	Phosphorylation	CINMAHVSPLRCTEG HHHCCCCCCCCCCHH		24719451
149	Phosphorylation	YAINGKISPQSNVDF EEECCEECCCCCCCE		28857561
172	Phosphorylation	PEWGLRDTALLEDLG CCCCCCCHHHHHHHH		20068231
180	Ubiquitination	ALLEDLGKASGLLLE HHHHHHHHHHCHHHH		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MTL26_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MTL26_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MTL26_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
DHSO_HUMAN	SORD	physical	22939629

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.