dbPTM

MTFR2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	MTFR2_MOUSE
UniProt AC	Q8VED8
Protein Name	Mitochondrial fission regulator 2
Gene Name	Mtfr2
Organism	Mus musculus (Mouse).
Sequence Length	361
Subcellular Localization	Mitochondrion . Associated with membranes.
Protein Description	May play a role in mitochondrial aerobic respiration essentially in the testis. Can also promote mitochondrial fission..
Protein Sequence	MPRDGTNEQRFLELPSPMSFILNILRNVLEYFGVPVDQDLLICQNKNCGSARSIVRIIGRRLPLKPCRRPHFELIPHVNSTESDDYELRVPSFADVLCVANDEEASCLRFRHSLWQKKEERKIAPFYPSKLTWDPSSPGLRQNKTETDDLPVNEAAIKKIAALEDELTFLRSQIAAIVAMQDLRESRETGFIDLSDEQVPPSSATTGLSVEPDHAPSVVLPPPPPPPPPPQFSLQPPSSLPMQPGSANTHDIDSLATEMERQLSGVKKTDDSHHSKSQRLRDVPNMLDVLKDVNKVRLRPVERSPGGRPVQKRKRRSSEWDPVSLISNALKQKFAFQDDSFDRENSSWECSPFSSPETSRF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
132	Phosphorylation	PFYPSKLTWDPSSPG CCCCCCCCCCCCCCC	27180971
136	Phosphorylation	SKLTWDPSSPGLRQN CCCCCCCCCCCCCCC	28066266
137	Phosphorylation	KLTWDPSSPGLRQNK CCCCCCCCCCCCCCC	28066266
276	Acetylation	TDDSHHSKSQRLRDV CCCCCCCHHHHHHHC	6566193
304	Phosphorylation	RLRPVERSPGGRPVQ CCCCCCCCCCCCCCC	29472430
317	Phosphorylation	VQKRKRRSSEWDPVS CCCCCCCCCCCCHHH	21082442
318	Phosphorylation	QKRKRRSSEWDPVSL CCCCCCCCCCCHHHH	25266776
324	Phosphorylation	SSEWDPVSLISNALK CCCCCHHHHHHHHHH	29119230
327	Phosphorylation	WDPVSLISNALKQKF CCHHHHHHHHHHHHH	29119230
340	Phosphorylation	KFAFQDDSFDRENSS HHCCCCCCCCCCCCC	28066266

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of MTFR2_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of MTFR2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of MTFR2_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of MTFR2_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of MTFR2_MOUSE

Related Literatures of Post-Translational Modification