| UniProt ID | MTCH2_MOUSE | |
|---|---|---|
| UniProt AC | Q791V5 | |
| Protein Name | Mitochondrial carrier homolog 2 | |
| Gene Name | Mtch2 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 303 | |
| Subcellular Localization |
Mitochondrion inner membrane Multi-pass membrane protein . |
|
| Protein Description | The substrate transported is not yet known. Induces mitochondrial depolarization (By similarity).. | |
| Protein Sequence | MADAASQVLLGSGLTILSQPLMYVKVLIQVGYEPLPPTIGRNIFGRQVCQLPGLFCYAQHIASIDGRRGLFTGLTPRLCSGVLGTVVHGKVLQYYQESEKPEELGSVTVQKEYSSSFDRVIKETTREMIARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIVTIYREEGIVGFFAGLIPRLLGDIISLWLCNSLAYLINTYALDSGVSTMNEMKSYSQAVTGFFASMLTYPFVLVSNLMAVNNCGLAGGSPPYSPIYTSWIDCWCMLQKAGNMSRGNSLFFRKVPCGKTYCYDLRMLI | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Acetylation | ------MADAASQVL ------CCHHHHHHH | 18.36 | - | |
| 49 | S-palmitoylation | NIFGRQVCQLPGLFC CCCCCCHHCCCCHHE | 2.32 | 28526873 | |
| 56 | S-palmitoylation | CQLPGLFCYAQHIAS HCCCCHHEEHHEEEC | 3.11 | 28526873 | |
| 79 | S-palmitoylation | TGLTPRLCSGVLGTV CCCCHHHCCCHHHHH | 3.34 | 28526873 | |
| 79 | S-nitrosocysteine | TGLTPRLCSGVLGTV CCCCHHHCCCHHHHH | 3.34 | - | |
| 79 | S-nitrosylation | TGLTPRLCSGVLGTV CCCCHHHCCCHHHHH | 3.34 | 21278135 | |
| 90 | Ubiquitination | LGTVVHGKVLQYYQE HHHHHHHHHHHHHHH | 25.54 | - | |
| 98 | Phosphorylation | VLQYYQESEKPEELG HHHHHHHCCCCHHHC | 35.08 | - | |
| 100 | Acetylation | QYYQESEKPEELGSV HHHHHCCCCHHHCCE | 67.99 | 23201123 | |
| 100 | Ubiquitination | QYYQESEKPEELGSV HHHHHCCCCHHHCCE | 67.99 | - | |
| 106 | Phosphorylation | EKPEELGSVTVQKEY CCCHHHCCEEEECHH | 27.52 | 29514104 | |
| 111 | Ubiquitination | LGSVTVQKEYSSSFD HCCEEEECHHCCCHH | 55.04 | - | |
| 114 | Phosphorylation | VTVQKEYSSSFDRVI EEEECHHCCCHHHHH | 22.16 | 28464351 | |
| 158 | Acetylation | QFIGRESKYCGLCDS HHHCCCCCCCCCCCE | 39.55 | 16916647 | |
| 160 | S-palmitoylation | IGRESKYCGLCDSIV HCCCCCCCCCCCEEE | 3.74 | 28526873 | |
| 163 | S-palmitoylation | ESKYCGLCDSIVTIY CCCCCCCCCEEEEEE | 2.04 | 28526873 | |
| 283 | Phosphorylation | GNMSRGNSLFFRKVP CCCCCCCCCEEEECC | 29.40 | 22324799 | |
| 296 | S-nitrosylation | VPCGKTYCYDLRMLI CCCCCEEEEEEHHCC | 2.29 | 21278135 | |
| 296 | S-palmitoylation | VPCGKTYCYDLRMLI CCCCCEEEEEEHHCC | 2.29 | 28526873 | |
| 296 | S-nitrosocysteine | VPCGKTYCYDLRMLI CCCCCEEEEEEHHCC | 2.29 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MTCH2_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MTCH2_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MTCH2_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of MTCH2_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Acetylation | |
| Reference | PubMed |
| "Substrate and functional diversity of lysine acetylation revealed bya proteomics survey."; Kim S.C., Sprung R., Chen Y., Xu Y., Ball H., Pei J., Cheng T.,Kho Y., Xiao H., Xiao L., Grishin N.V., White M., Yang X.-J., Zhao Y.; Mol. Cell 23:607-618(2006). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-158, AND MASS SPECTROMETRY. | |
