MT1M_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MT1M_HUMAN
• UniProt AC: Q8N339
• Protein Name: Metallothionein-1M
• Gene Name: MT1M
• Organism: Homo sapiens (Human).
• Sequence Length: 61
• Protein Description: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids..
• Protein Sequence: MDPNCSCTTGVSCACTGSCTCKECKCTSCKKSCCSCCPVGCAKCAHGCVCKGTLENCSCCA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
8	Phosphorylation	MDPNCSCTTGVSCAC CCCCCCCCCCCCEEE	15.42	-
9	Phosphorylation	DPNCSCTTGVSCACT CCCCCCCCCCCEEEC	39.66	-
18	Phosphorylation	VSCACTGSCTCKECK CCEEECCCEECCCCC	6.52	-
32	Phosphorylation	KCTSCKKSCCSCCPV CCCCCCCCCCCCCCC	13.07	22777824
35	Phosphorylation	SCKKSCCSCCPVGCA CCCCCCCCCCCCCCC	24.07	28258704

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MT1M_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MT1M_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MT1M_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RELB_HUMAN	RELB	physical	21988832

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.