MROH6_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MROH6_HUMAN
• UniProt AC: A6NGR9
• Protein Name: Maestro heat-like repeat-containing protein family member 6
• Gene Name: MROH6
• Organism: Homo sapiens (Human).
• Sequence Length: 719
• Protein Sequence: MAGGVWGRSRAREAPVGALTLTALTEGIRARQGQPQGPPSAGPQPKSWEVKPEAEPQTQALTAPSEAEPGRGATVPEAGSEPCSLNSALEPAPEGPHQVPQSSWEEGVLADLALYTAACLEEAGFAGTQATVLTLSSALEARGERLEDQVHALVRGLLAQVPSLAEGRPWRAALRVLSALALEHARDVVCALLPRSLPADRVAAELWRSLSRNQRVNGQVLVQLLWALKGASGPEPQALAATRALGEMLAVSGCVGATRGFYPHLLLALVTQLHKLARSPCSPDMPKIWVLSHRGPPHSHASCAVEALKALLTGDGGRMVVTCMEQAGGWRRLVGAHTHLEGVLLLASAMVAHADHHLRGLFADLLPRLRSADDPQRLTAMAFFTGLLQSRPTARLLREEVILERLLTWQGDPEPTVRWLGLLGLGHLALNRRKVRHVSTLLPALLGALGEGDARLVGAALGALRRLLLRPRAPVRLLSAELGPRLPPLLDDTRDSIRASAVGLLGTLVRRGRGGLRLGLRGPLRKLVLQSLVPLLLRLHDPSRDAAESSEWTLARCDHAFCWGLLEELVTVAHYDSPEALSHLCCRLVQRYPGHVPNFLSQTQGYLRSPQDPLRRAAAVLIGFLVHHASPGCVNQDLLDSLFQDLGRLQSDPKPAVAAAAHVSAQQVAMLARARGCPRGPRLLRIAPRPARPPPVFADSPFQRRSVAGRWGCSGPRRA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Phosphorylation	AGGVWGRSRAREAPV CCCCCCCCCCCCCCC		29449344
46	Ubiquitination	PSAGPQPKSWEVKPE CCCCCCCCCEECCCC		22817900
51	Ubiquitination	QPKSWEVKPEAEPQT CCCCEECCCCCCCCC		21906983
262	Phosphorylation	VGATRGFYPHLLLAL HHHHCCCHHHHHHHH		-
282	Phosphorylation	KLARSPCSPDMPKIW HHHCCCCCCCCCEEE		25159151
416	Phosphorylation	WQGDPEPTVRWLGLL CCCCCCCCHHHHHHH		-
496	Phosphorylation	LLDDTRDSIRASAVG CCCCCHHHHHHHHHH		-
507	Phosphorylation	SAVGLLGTLVRRGRG HHHHHHHHHHHCCCC		-
531	Phosphorylation	LRKLVLQSLVPLLLR HHHHHHHHHHHHHHH		-
549	Phosphorylation	PSRDAAESSEWTLAR CCCCHHHCCCHHHHH		29414761
601	Phosphorylation	GHVPNFLSQTQGYLR CCCCCHHHHCCCCCC		22496350
603	Phosphorylation	VPNFLSQTQGYLRSP CCCHHHHCCCCCCCC		22496350

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MROH6_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MROH6_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MROH6_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of MROH6_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.