MROH5_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MROH5_HUMAN
• UniProt AC: Q6ZUA9
• Protein Name: Maestro heat-like repeat family member 5
• Gene Name: MROH5
• Organism: Homo sapiens (Human).
• Sequence Length: 1318
• Protein Sequence: MDRQCSERPYSCTPTGRVSSAVSQNSRISPPVSTSMKDSSCMKVHQDSARRDRWSHPTTILLHKSQSSQATLMLQEHRMFMGEAYSAATGFKMLQDMNSADPFHLKYIIKKIKNMAHGSPKLVMETIHDYFIDNPEISSRHKFRLFQTLEMVIGASDVLEETWEKTFTRLALENMTKATELEDIYQDAASNMLVAICRHSWRVVAQHLETELLTGVFPHRSLLYVMGVLSSSEELFSQEDKACWEEQLIQMAIKSVPFLSTDVWSKELLWTLTTPSWTQQEQSPEKAFLFTYYGLILQAEKNGATVRRHLQALLETSHQWPKQREGMALTLGLAATRHLDDVWAVLDQFGRSRPIRWSLPSSSPKNSEDLRWKWASSTILLAYGQVAAKARAHILPWVDNIVSRMVFYFHYSSWDETLKQSFLTATLMLMGAVSRSEGAHSYEFFQTSELLQCLMVLMEKEPQDTLCTRSRQQAMHIASSLCKLRPPIDLERKSQLLSTCFRSVFALPLLDALEKHTCLFLEPPNIQLWPVARERAGWTHQGWGPRAVLHCSEHLQSLYSRTMEALDFMLQSLIMQNPTADELHFLLSHLYIWLASEKAHERQRAVHSCMILLKFLNHNGYLDPKEDFKRIGQLVGILGMLCQDPDRATQRCSLEGASHLYQLLMCHKTGEALQAESQAPKELSQAHSDGAPLWNSRDQKATPLGPQEMAKNHIFQLCSFQVIKDIMQQLTLAELSDLIWTAIDGLGSTSPFRVQAASEMLLTAVQEHGAKLEIVSSMAQAIRLRLCSVHIPQAKEKTLHAITLLARSHTCELVATFLNISIPLDSHTFQLWRALGAGQPTSHLVLTTLLACLQERPLPTGASDSSPCPKEKTYLRLLAAMNMLHELQFAREFKQAVQEGYPKLFLALLTQMHYVLELNLPSEPQPKQQAQEAAVPSPQSCSTSLEALKSLLSTTGHWHDFAHLELQGSWELFTTIHTYPKGVGLLARAMVQNHCRQIPAVLRQLLPSLQSPQERERKVAILILTKFLYSPVLLEVLPKQAALTVLAQGLHDPSPEVRVLSLQGLSNILFHPDKGSLLQGQLRPLLDGFFQSSDQVIVCIMGTVSDTLHRLGAQGTGSQSLGVAISTRSFFNDERDGIRAAAMALFGDLVAAMADRELSGLRTQVHQSMVPLLLHLKDQCPAVATQAKFTFYRCAVLLRWRLLHTLFCTLAWERGLSARHFLWTCLMTRSQEEFSIHLSQALSYLHSHSCHIKTWVTLFIGHTICYHPQAVFQMLNAVDTNLLFRTFEHLRSDPEPSIREFATSQLSFLQKVSARPKQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
119	Phosphorylation	IKNMAHGSPKLVMET HHHHCCCCCCHHHHH		28348404
166	Phosphorylation	LEETWEKTFTRLALE HHHHHHHHHHHHHHH		22210691
168	Phosphorylation	ETWEKTFTRLALENM HHHHHHHHHHHHHHC		22210691
176	Phosphorylation	RLALENMTKATELED HHHHHHCCCCHHHHH		22210691
336	Phosphorylation	LTLGLAATRHLDDVW HHHHHHHHHCHHHHH		-
408	Phosphorylation	IVSRMVFYFHYSSWD HHHHHHHHHHHCCCC		20049867
411	Phosphorylation	RMVFYFHYSSWDETL HHHHHHHHCCCCHHH		20049867
412	Phosphorylation	MVFYFHYSSWDETLK HHHHHHHCCCCHHHH		20049867
413	Phosphorylation	VFYFHYSSWDETLKQ HHHHHHCCCCHHHHH		20049867
421	Phosphorylation	WDETLKQSFLTATLM CCHHHHHHHHHHHHH		20049867
424	Phosphorylation	TLKQSFLTATLMLMG HHHHHHHHHHHHHHH		20049867
426	Phosphorylation	KQSFLTATLMLMGAV HHHHHHHHHHHHHHH		20049867
436	Phosphorylation	LMGAVSRSEGAHSYE HHHHHHCCCCCCCCC		27732954
441	Phosphorylation	SRSEGAHSYEFFQTS HCCCCCCCCCHHCHH		27732954
442	Phosphorylation	RSEGAHSYEFFQTSE CCCCCCCCCHHCHHH		27732954
447	Phosphorylation	HSYEFFQTSELLQCL CCCCHHCHHHHHHHH		27732954
448	Phosphorylation	SYEFFQTSELLQCLM CCCHHCHHHHHHHHH		27732954
465	Phosphorylation	MEKEPQDTLCTRSRQ HHCCCCCCCCCHHHH		30257219
468	Phosphorylation	EPQDTLCTRSRQQAM CCCCCCCCHHHHHHH		30257219
503	Phosphorylation	LLSTCFRSVFALPLL HHHHHHHHHHHHHHH		-
560	Phosphorylation	EHLQSLYSRTMEALD HHHHHHHHHHHHHHH		24719451
625	Acetylation	HNGYLDPKEDFKRIG CCCCCCCHHHHHHHH		18584535
1159	Phosphorylation	AMADRELSGLRTQVH HHHHHHHHCHHHHHH		24719451
1224	Phosphorylation	SARHFLWTCLMTRSQ CHHHHHHHHHHCCCH		22210691
1243	Phosphorylation	IHLSQALSYLHSHSC HHHHHHHHHHHHCCC		22210691
1247	Phosphorylation	QALSYLHSHSCHIKT HHHHHHHHCCCCHHH		22210691

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MROH5_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MROH5_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MROH5_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of MROH5_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.