dbPTM

MRM3_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	MRM3_DROME
UniProt AC	Q9VW14
Protein Name	rRNA methyltransferase 3, mitochondrial {ECO:0000250\|UniProtKB:Q9HC36}
Gene Name	CG14100
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	407
Subcellular Localization	Mitochondrion .
Protein Description	S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1580 (Gm1580) in the mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a conserved modification in the peptidyl transferase domain of the mtLSU rRNA..
Protein Sequence	MLCNIFKRSLQANIRNVNNLNVLRLSSSSGPRGEIQDALDIEANLFGNSDLRHEPMNTREALRKNRFAGRKPKVPFASVASRNLSAPSNPAPRVAPTPAPVIKDNELNLEFVRLTLQDPLTSTLLTTVRSRKRRDKNRQIIVEGRRLIQEALQCGLKMEVLLFSQKDQLALVKEEVGVAQVETGTKIYKVPQHDLKTWSSLVTPPGLMAIFDRPSDKGLEKNLAEQQRLGSQPFPITVVCDNIREPNNLGSIIRTCAALPCSQVVVTHGCCDPWESKALRGGCGGQFRVPIRDDVTWDELALTIPPEAADDCHVFIAETNQRKRENNQTIDYADIKGLGAHNLLIIGGESHGVSEEAYRFLNLVGGKGKCIYIPLAAGIDSLNVASALTLLLFELRRKLIHQASEKE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
78	Phosphorylation	KPKVPFASVASRNLS CCCCCHHHHHCCCCC		22817900

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of MRM3_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of MRM3_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of MRM3_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of MRM3_DROME !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of MRM3_DROME

Related Literatures of Post-Translational Modification